在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Death-associated protein kinase 3 (Dapk3)

Recombinant Mouse Death-associated protein kinase 3 (Dapk3)

  • 中文名稱：
    Recombinant Mouse Death-associated protein kinase 3(Dapk3)
  • 貨號：
    CSB-YP006501MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Death-associated protein kinase 3(Dapk3)
  • 貨號：
    CSB-EP006501MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Death-associated protein kinase 3(Dapk3)
  • 貨號：
    CSB-EP006501MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Death-associated protein kinase 3(Dapk3)
  • 貨號：
    CSB-BP006501MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Death-associated protein kinase 3(Dapk3)
  • 貨號：
    CSB-MP006501MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Dapk3; Zipk; Death-associated protein kinase 3; DAP kinase 3; EC 2.7.11.1; DAP-like kinase; Dlk; MYPT1 kinase; ZIP-kinase
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-448
  • 氨基酸序列
    MSTFRQEDVE DHYEMGEELG SGQFAIVRKC QQKGTGMEYA AKFIKKRRLP SSRRGVSREE IEREVSILRE IRHPNIITLH DVFENKTDVV LILELVSGGE LFDFLAEKES LTEDEATQFL KQILDGVHYL HSKRIAHFDL KPENIMLLDK HAASPRIKLI DFGIAHRIEA GSEFKNIFGT PEFVAPEIVN YEPLGLEADM WSIGVITYIL LSGASPFLGE TKQETLTNIS AVNYDFDEEY FSSTSELAKD FIRRLLVKDP KRRMTIAQSL EHSWIKVRRR EDGARKPERR RLRAARLREY SLKSHSSMPR NTSYASFERF SRVLEDVAAA EQGLRELQRG RRQCRERVCA LRAAAEQREA RCRDGSAGLG RDLRRLRTEL GRTEALRTRA QEEARAALLG AGGLKRRLCR LENRYDALAA QVAAEVQFVR DLVRALEQER LQAECGVR
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in formation of promyelocytic leukemia protein nuclear body (PML-NB). Involved in apoptosis involving PAWR which mediates cytoplasmic relocation; in vitro phosphorylates PAWR. Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton such as in regulation of cell polarity and cell migration. Positively regulates canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2; disrupts the NLK-TCF7L2 complex thereby influencing the phosphorylation of TCF7L2 by NLK. Phosphorylates STAT3 and enhances its transcriptional activity. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome, RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition.
  • 基因功能參考文獻：
    1. Cellular and mouse modeling studies show that DAPK3 is a tumor suppressor gene and is important in early development. PMID: 25304685
    2. DAPK3 plays a central role in preventing miR-17/miR-20a depletion-induced genome instability and in miR-17/miR-20a overexpression-triggered tumor formation. PMID: 26117336
    3. The C-terminal domain (NLS2 motif)of ZIPK of murine is nonfunctional for transport. PMID: 20854903
    4. ZIPK may act as a cardiac RLC kinase and thereby affect contractility. PMID: 20038585
    5. murine ZIPK underwent specific divergence from a conserved consensus PMID: 17953487

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Nucleus, PML body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
  • 組織特異性：
    Highly expressed in heart, brain, lung, skeletal muscle, kidney and testis. Lower levels in liver and spleen.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 给我免费的视频在线观看| 亚洲精品毛片一区二区三区| 麻花传媒在线mv免费观看视频| 国产偷国产偷亚洲清高app| 五月av综合av国产av| 疯狂做受xxxx高潮不断| 精品系列无码一区二区三区| 国产一区二区三区不卡在线看| 亚洲免费观看视频| 男女性爽大片视频| 亚洲精品国产成人精品| 国产精品真实灌醉女在线播放| 国产高清在线精品一区二区三区 | 国产欧美丝袜在线二区| 综合五月激情二区视频| 久久99国产综合精品免费| 日韩精品无码中文字幕一区二区| 日韩 高清 无码 人妻| 国产成人精品一区二区三区| 国产精品美女久久久久久2018| 亚洲国产制服丝袜无码av| 国产av毛片亚洲含羞草社| 欧美日韩亚洲国产欧美电影| 天天躁日日躁很很很躁| 欧美网站免费观看在线| 国产成 人 综合 亚洲网站| 动漫精品中文无码卡通动漫| 日韩人妻一区二区三区蜜桃视频| 久久国产精品免费一区二区三区 | 久久久www成人免费毛片| 国产成人综合在线女婷五月99播放| 伊人大杳焦在线| 午夜免费男女aaaa片| 香港三级日本三级妇三级| 99久久精品午夜一区二区 | 精品蜜臀久久久久99网站| 日韩视频在线观看| 强迫大乳人妻中文字幕| 久久av高潮av无码av| 在线观看特色大片免费网站| 青青青国产免a在线观看|