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  4. Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9 (Crcp)

Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9 (Crcp)

  • 中文名稱：
    Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9(Crcp)
  • 貨號：
    CSB-YP005945MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9(Crcp)
  • 貨號：
    CSB-EP005945MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9(Crcp)
  • 貨號：
    CSB-EP005945MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9(Crcp)
  • 貨號：
    CSB-BP005945MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse DNA-directed RNA polymerase III subunit RPC9(Crcp)
  • 貨號：
    CSB-MP005945MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Crcp
  • Uniprot No.：
  • 別名：
    Crcp; DNA-directed RNA polymerase III subunit RPC9; RNA polymerase III subunit C9; Calcitonin gene-related peptide-receptor component protein; CGRP-RCP; CGRP-receptor component protein; CGRPRCP
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-148
  • 氨基酸序列
    MEVKDANAAL LSNYEVFQLL TDLKEQRKES GKNKHSAGQQ NLNAITYETL KYISKTPCRN QSPAIVQEFL TAMKSHKLTK AEKLQLLNHR PMTAVEIQLM VEESEERLTE EQIEALLHTV TSILPAGPED EQSKSTSNDV AMEEEEPA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway.; Accessory protein for the calcitonin gene-related peptide (CGRP) receptor. It modulates CGRP responsiveness in a variety of tissues.
  • 基因功能參考文獻：
    1. CGRP can inhibit microglia activation in vivo in EAE. CGRP and its receptor may represent novel protective factors in EAE. PMID: 24746422
    2. The mouse cDNA for calcitonin receptor-like receptor (CRLR) was cloned. The signal transduction mechanism through the CGRP receptor was studied. mCRLR is a 462-amino acid G-protein-coupled heptahelical receptor. PMID: 12147211
  • 亞細胞定位：
    Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Eukaryotic RPC9 RNA polymerase subunit family
  • 組織特異性：
    Ubiquitous. Most prevalent in testis.
  • 數據庫鏈接：


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