在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Cysteinyl leukotriene receptor 2 (Cysltr2), partial

Recombinant Mouse Cysteinyl leukotriene receptor 2 (Cysltr2), partial

  • 中文名稱：
    Recombinant Mouse Cysteinyl leukotriene receptor 2(Cysltr2),partial
  • 貨號：
    CSB-YP006466MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cysteinyl leukotriene receptor 2(Cysltr2),partial
  • 貨號：
    CSB-EP006466MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cysteinyl leukotriene receptor 2(Cysltr2),partial
  • 貨號：
    CSB-EP006466MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Cysteinyl leukotriene receptor 2(Cysltr2),partial
  • 貨號：
    CSB-BP006466MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cysteinyl leukotriene receptor 2(Cysltr2),partial
  • 貨號：
    CSB-MP006466MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cysltr2; Cyslt2; Cysteinyl leukotriene receptor 2; CysLTR2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
  • 基因功能參考文獻：
    1. CysLT2R signaling, IL-33-dependent group 2 innate lymphoid cell expansion, and IL-33-driven mast cell activation are necessary for induction of type 2 immunopathology and aspirin sensitivity. CysLT2R-targeted drugs may interrupt these processes. PMID: 29282304
    2. It plays a critical role in Ab1e42-induced neurotoxicity. PMID: 24269024
    3. The CysLT(1) and CysLT(2) receptors were primarily localized in neurons, microglia and neutrophils PMID: 23132680
    4. Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury. PMID: 24285579
    5. LTC4 activates mouse platelets exclusively through CysLT2R. LTC4/CysLT2R signaling required an autocrine ADP-mediated response through P2Y12 receptors. PMID: 24244016
    6. CysLT1R, CysLT2R and GPR17 might be involved in the MPTP-induced Parkinson disease damage in mice. PMID: 23505108
    7. CysLT2R negatively regulates the development of cys-LT-dependent T helper cell (Th)2 pulmonary inflammation by inhibiting both CysLT1R signaling and house dust mite-induced LTC4S-dependent cell surface expression of CysLT1R on dendritic cells. PMID: 23002438
    8. These findings establish a role for eosinophil-derived cysteinyl leukotriene and the CysLT(2)R in the hyperkeratosis and fibrosis of allergic skin inflammation. PMID: 22416124
    9. Results implicate the CysLT(2)R in the progression of ischemic retinopathy. PMID: 22131271
    10. These results suggest that a lack of neuronal expression of CysLTR in the murine colonic myenteric plexus attenuates colitis disease progression. PMID: 21641390
    11. findings show that CysLT1 receptor attenuates while CysLT2 receptor facilitates oxygen glucose deprivation -induced PC12 cell death PMID: 16756959
    12. CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells. PMID: 17693579
    13. Endothelium-targeted overexpression of CysLT2R aggravates myocardial ischemia-reperfusion injury by increasing endothelial permeability and by accelerating left ventricular remodeling, and impaired cardiac performance. PMID: 18276782

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Widely expressed at low levels, with highest expression in the spleen, thymus and adrenal gland, and lower in the kidney, brain and peripheral blood leukocytes.
  • 數據庫鏈接：


主站蜘蛛池模板： 美国人性欧美xxxx| 国产精品女人呻吟在线观看| 夜晚成人18禁区导航网站| 成人毛片100免费观看| 亚洲乱码中文字幕综合| 深夜国产一区二区三区在线看| 欧美最猛性xxxxx大叫| 无码日韩精品一区二区三区免费| 久久99精品久久久大学生| 国产精品成人久久电影| 午夜福利国产成人a∨在线观看| 中文字幕乱码熟妇五十中出色欲| 18禁裸体动漫美女无遮挡网站 | 欧洲美熟女乱又伦av| 一区二区三区内射美女毛片| 亚洲成av人片一区二区密柚| 亚洲精品色情aⅴ色戒| h人成在线看免费视频| 国产成人无码精品久久久露脸| 人人妻人人澡人人爽人人精品浪潮| 国产午夜精品一区二区三区极品| 国语自产偷拍精品视频蜜芽| 亚洲精品中文字幕无码蜜桃| 日本熟妇人妻xxxxx| 国产精品无打码在线播放| 亚洲欧洲美洲在线观看| 国产乱子影视频上线免费观看| 日本一区二区更新不卡| 国产成人精品一区二区不卡| 国产交换配乱婬视频| 婷婷国产成人精品视频| 少妇做爰又色又紧夜视频| 波多野结衣潮喷视频无码42| 精品人妻午夜一区二区三区四区| 男人的好看免费观看在线视频| 日日摸日日碰夜夜爽无码| 久久精品无码专区免费| 热久久美女精品天天吊色| 性国产牲交xxxxx视频| 日韩人妻无码免费视频一区二区三区 | 午夜福利伦伦电影理论片在线观看 |