在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Contactin-1 (Cntn1), partial

Recombinant Mouse Contactin-1 (Cntn1), partial

  • 中文名稱：
    Recombinant Mouse Contactin-1(Cntn1) ,partial
  • 貨號(hào)：
    CSB-YP005686MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Contactin-1(Cntn1) ,partial
  • 貨號(hào)：
    CSB-EP005686MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Contactin-1(Cntn1) ,partial
  • 貨號(hào)：
    CSB-EP005686MO-B
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Contactin-1(Cntn1) ,partial
  • 貨號(hào)：
    CSB-BP005686MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Contactin-1(Cntn1) ,partial
  • 貨號(hào)：
    CSB-MP005686MO
  • 說(shuō)明書：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cntn1Contactin-1; Neural cell surface protein F3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.
  • 基因功能參考文獻(xiàn)：
    1. Data indicate that Contactin-1 expression is dependent upon EBF factors; Cntn1 gene belongs to the expanding regulatory cascade driven by these transcriptional regulators so that changes in its activation may contribute to the Ebf2 null mutant phenotype PMID: 25820347
    2. It plays a role in hippocampal synaptic plasticity and memory also in aged mice, suggesting that it acts on molecular pathways related to apoptosis and amyloid-beta production. PMID: 25659859
    3. The F3/contactin plays a role in promoting adult hippocampal neurogenesis and that this effect correlates with improved synaptic function and memory. PMID: 23939883
    4. Contactin-1 has roles in regulating myelination and nodal/paranodal domain organization in the central nervous system PMID: 24385581
    5. In developing cerebral cortex and basal ganglia the F3/Contactin gene is mostly activated during early commitment of neuronal precursors. PMID: 22579730
    6. The phenotype of the Cntn1 mice arises from dysfunction in the brain, spinal cord or peripheral nervous system. PMID: 22242131
    7. Data show that TAG1 and F3 act antagonistically to control SHH-induced proliferation: F3 suppresses SHH-induced GNP proliferation and induces differentiation, whereas TAG1 antagonises F3. PMID: 21205796
    8. The structural and functional properties, the mechanisms driving the regulated expression and on the developmental role of mouse F3/Contactin is reviewed. PMID: 19372728
    9. these findings indicate that precise spatio-temporal regulation of TAG-1 and F3/contactin expression is critical for normal cerebellar morphogenesis PMID: 12441289
    10. F3/contactin and caspr/paranodin traffic to the cell surface via a non-conventional pathway PMID: 12972410
    11. Deficits in sensorimotor function, homing behavior, and motor activity in transgenic F3/contactin mice indicate that the finely coordinated expression of F3/contactin is key to the functional, as well as morphological maturation of the cerebellum. PMID: 14667450
    12. These data provide evidence of a role for contactin in selectively regulating the cell surface expression and current densities of TTX-R but not TTX-S Na+ channel isoforms in nociceptive DRG neurons. PMID: 16029194
    13. Contactin-1 is a functional receptor for neuroregulatory chondroitin sulfate-E. PMID: 19075012
    14. Thus, our results suggest a contribution by DRG Na(v)1.6, and possibly Contactin to neuropathic pain in the neuroma model in mice. PMID: 19524556

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Immunoglobulin superfamily, Contactin family
  • 組織特異性：
    Expressed in the ovary and in Sertoli cells of the testis.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 超碰曰口干天天种夜夜爽| 国产精品成人一区无码| av在线播放无码线| 在线 无码 中文字幕 强 乱 | 亚洲日本一区二区三区在线| 大又大粗又爽又黄少妇毛片| 日本黄页网站免费观看| 亚洲欧美色αv在线影视| 人妻老妇乱子伦精品无码专区| 欧美真人做爰在线观看| 特级精品毛片免费观看| 国产毛a片啊久久久久久保和丸| 国产69精品久久久久久妇女迅雷| 久久精品国产国产精品四凭| 国产成人精品一区二区三区无码| 国产精品免费一区二区三区四区| 日韩人妻精品一区二区三区视频| 久久天天躁狠狠躁夜夜夜| 日本少妇寂寞少妇aaa| 无码人妻精品一区二区蜜桃色欲| 日本最新免费二区| 色www永久免费视频首页| 久久被窝亚洲精品爽爽爽| 人妻无码中文久久久久专区| 性久久久久久| 无码人妻精品丰满熟妇区| 中国国产1级毛卡片| 国产精品无码v在线观看| 人妻人人澡人人添人人爽| av毛片无码中文字幕不卡| 亚洲精品色情app在线下载观看| 67194熟妇在线观看线路| 日韩精品无码视频一区二区蜜桃| 久久久水蜜桃国产成人网站| 国产精品一区二区av交换| 成人免费国产精品视频| 中文在线а√在线天堂中文| 久久人妻国产精品31| 四虎永久地址www成人| 无码人妻品一区二区三区精99| 亚洲婷婷开心色四房播播|