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  4. Recombinant Mouse Coiled-coil domain-containing protein 88B (Ccdc88b), partial

Recombinant Mouse Coiled-coil domain-containing protein 88B (Ccdc88b), partial

  • 中文名稱：
    Recombinant Mouse Coiled-coil domain-containing protein 88B(Ccdc88b) ,partial
  • 貨號：
    CSB-YP700123MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Coiled-coil domain-containing protein 88B(Ccdc88b) ,partial
  • 貨號：
    CSB-EP700123MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Coiled-coil domain-containing protein 88B(Ccdc88b) ,partial
  • 貨號：
    CSB-EP700123MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Coiled-coil domain-containing protein 88B(Ccdc88b) ,partial
  • 貨號：
    CSB-BP700123MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Coiled-coil domain-containing protein 88B(Ccdc88b) ,partial
  • 貨號：
    CSB-MP700123MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ccdc88b
  • Uniprot No.：
  • 別名：
    Ccdc88b; Ccdc88Coiled-coil domain-containing protein 88B; Gipie; Hook-related protein 3; HkRP3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a positive regulator of T-cell maturation and inflammatory function. Required for several functions of T-cells in both the CD4(+) and the CD8(+) compartments and this includes expression of cell surface markers of activation, proliferation, and cytokine production in response to specific or non-specific stimulation and during the course of infection with the mouse malaria parasite Plasmodium berghei. Enhances NK cell cytotoxicity by positively regulating polarization of microtubule-organizing center (MTOC) to cytotoxic synapse, lytic granule transport along microtubules, and dynein-mediated clustering to MTOC. Interacts with HSPA5 and stabilizes the interaction between HSPA5 and ERN1, leading to suppression of ERN1-induced JNK activation and endoplasmic reticulum stress-induced apoptosis.
  • 基因功能參考文獻：
    1. A critical function of CCDC88B in colonic inflammation PMID: 29030607
    2. These results identify CCDC88B as a novel and important regulator of T cell function. PMID: 25403443
  • 亞細胞定位：
    Membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center. Endoplasmic reticulum. Golgi apparatus. Cytoplasm.
  • 蛋白家族：
    CCDC88 family
  • 組織特異性：
    Abundantly expressed in immune cells, including both CD4(+) and CD8(+) T-cells and in myeloid cells (at protein level). Expressed in endothelium (at protein level). Expressed specifically in spleen, bone marrow, lymph nodes and thymus. Expressed in liver
  • 數據庫鏈接：

    KEGG: mmu:78317

    UniGene: Mm.329596



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