在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Claudin-18 (Cldn18), partial

Recombinant Mouse Claudin-18 (Cldn18), partial

  • 中文名稱：
    Recombinant Mouse Claudin-18(Cldn18),partial
  • 貨號：
    CSB-YP005498MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Claudin-18(Cldn18),partial
  • 貨號：
    CSB-EP005498MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Claudin-18(Cldn18),partial
  • 貨號：
    CSB-EP005498MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Claudin-18(Cldn18),partial
  • 貨號：
    CSB-BP005498MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Claudin-18(Cldn18),partial
  • 貨號：
    CSB-MP005498MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cldn18; Claudin-18
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
  • 基因功能參考文獻：
    1. The presented data substantiate the hypothesis that claudin-18 is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18. These data also suggest that the loss of claudin-18 is associated with increased sensitization to aeroantigens and airway responsiveness PMID: 27215490
    2. The claudin-18 knockout mice exhibited decreased P2X7 mRNA transcript abundance as measured by mRNA expression microarray PMID: 27663455
    3. CLDN18 deficiency results in epithelial barrier dysfunction, injury, and impaired alveolarization in mice. PMID: 24787463
    4. Identify a role for claudin 18 in alveolar fluid homeostasis beyond its direct contributions to barrier properties. PMID: 24588076
    5. we conclude that the estrogen effects on osteoclasts may in part be mediated via regulation of Cldn-18 signaling PMID: 23299504
    6. Claudin-18 is expressed at the variety of epithelial tissues in inner ear including Organ of Corti, stria vascularis, Reissner's membrane, spiral limbus, vestibular sensory epithelia, and dark cell area. PMID: 14698084
    7. Cldn-18 is a novel negative regulator of bone resorption and osteoclast differentiation PMID: 22437732
    8. Claudin-18 forms a paracellular barrier against H(+) in the stomach. Deficiency causes paracellular H(+) leak, up-regulation of proinflammatory cytokines, recruitment of neutrophils, and atrophic gastritis. PMID: 22079592
    9. Increased expression of claudin-18 is associated with ulcerative colitis. PMID: 18831034

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Claudin family
  • 組織特異性：
    Isoform A1.1: Expressed in lung. Isoform A1.2: Expressed in lung. Isoform A2.1: Expressed in stomach. Isoform A2.2: Expressed in stomach.
  • 數據庫鏈接：


主站蜘蛛池模板： 性史性农村dvd毛片| 中本亚洲欧美国产日韩| 欧美xxxx做受视频| 特级精品毛片免费观看| 野花社区在线观看视频| 成人亚洲精品久久久久软件| 久久精品国产亚洲夜色av网站| 午夜视频在线观看免费完整版| 亚洲中文字幕无码久久| 久激情内射婷内射蜜桃| 国产婷婷成人久久av免费高清| 亚洲国产成人精品福利| 国产精品乱码久久久久软件| 日本爽爽爽爽爽爽在线观看免 | 久久成人a毛片免费观看网站| 日韩中文字幕在线一区二区三区| av无码人妻一区二区三区牛牛| 久久成人网站亚洲综合| 国产丝袜视频一区二区三区| 国产私人尤物无码不卡| 久久www成人看片免费不卡| 亚洲欲色欲香天天综合网| 西欧free性满足hd老熟妇| 最新69国产成人精品视频免费| 色香阁综合无码国产在线| 久久久久高潮毛片免费全部播放| 亚洲成av人在线视| 欧美品无码一区二区三区在线蜜桃 | 22222se男人的天堂| 欧美乱码精品一区二区三区| 性国产牲交xxxxx视频| 久久亚洲熟女cc98cm| 人妻少妇精品无码专区| 亚洲美女高清无水av| 欧美黑人激情性久久| 天天爽夜夜爽人人爽一区二区| 亚洲中文在线播放一区| 蜜臀少妇人妻在线| 国产精品妇女一二三区| 99re6热视频这里只精品首页| 18禁黄网站禁片免费观看女女|