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  4. Recombinant Mouse Centromere protein U (Mlf1ip)

Recombinant Mouse Centromere protein U (Mlf1ip)

  • 中文名稱：
    Recombinant Mouse Centromere protein U(Mlf1ip)
  • 貨號：
    CSB-YP806488MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Centromere protein U(Mlf1ip)
  • 貨號：
    CSB-EP806488MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Centromere protein U(Mlf1ip)
  • 貨號：
    CSB-EP806488MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Centromere protein U(Mlf1ip)
  • 貨號：
    CSB-BP806488MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Centromere protein U(Mlf1ip)
  • 貨號：
    CSB-MP806488MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Cenpu
  • Uniprot No.：
  • 別名：
    Cenpu; Mlf1ipCentromere protein U; CENP-U; MLF1-interacting protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-410
  • 氨基酸序列
    MAARRSLRYS GNPGAKHSKN TLRSTYSRKQ KAGPKPRPKD VFDFSNNSDA SSIPGALEEE EETYETFDPP LHSTAIYAED ELSKHCVSSS SLATHRGKAS RNLDPSEDEA SGNESIKVST KKPRRKLEPI SGESDSSADD VRRRVASAEG PRSQQRQAAP AAPSPPERPA EPVTPRRTRL HSAQLSPVDE TPATQSQLKT QKKVRPSPGR RKRPRRGHTD TDGSESMHIW CLEGKRQSDI TELDVILSVF EKTFLEYKQR VESESCNQAI NKFYFKMKGE LIRMLKEAQM LKALKMKNTK IIANMEKKRQ RLIEVQDELI RLEPQLKQLQ TKYDDLKERK SSLKKSKHFL SNLKQLCQDY SNVQEKGPKG TGKYDSSSLP ALLFKARSIL GAENHLRTIN YQLGKLLELD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
  • 基因功能參考文獻：
    1. MLF1IP transgenic mice developed polycythemia vera (PV)-like symptoms based on the analysis of hematological features, suggesting that MLF1IP is partially involved in the pathogenesis of PV. PMID: 28173615
    2. MLF1-IP expression at about 50% of its normal level is sufficient to sustain mice life and the development of their immune system without apparent abnormalities. PMID: 23724000
  • 亞細胞定位：
    Cytoplasm. Nucleus. Chromosome, centromere, kinetochore.
  • 蛋白家族：
    CENP-U/AME1 family
  • 組織特異性：
    Testis, spleen, heart, kidney, liver, lung, brain and CFU-E erythroid precursor cells.
  • 數據庫鏈接：


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