在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Cardiotrophin-1 (Ctf1)

Recombinant Mouse Cardiotrophin-1 (Ctf1)

  • 中文名稱：
    Recombinant Mouse Cardiotrophin-1(Ctf1)
  • 貨號：
    CSB-YP733705MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cardiotrophin-1(Ctf1)
  • 貨號：
    CSB-EP733705MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cardiotrophin-1(Ctf1)
  • 貨號：
    CSB-EP733705MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Cardiotrophin-1(Ctf1)
  • 貨號：
    CSB-BP733705MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cardiotrophin-1(Ctf1)
  • 貨號：
    CSB-MP733705MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ctf1Cardiotrophin-1; CT-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-203
  • 氨基酸序列
    MSQREGSLED HQTDSSISFL PHLEAKIRQT HNLARLLTKY AEQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSVLPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP GPEPVTVATL FTANSTAGIF SAKVLGFHVC GLYGEWVSRT EGDLGQLVPG GVA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
  • 基因功能參考文獻：
    1. These results suggest that CT-1 may be a potent candidate for the early prevention and treatment of Alzheimer disease. PMID: 28731433
    2. Identify cardiotrophin-1 as a powerful cytokine promoting mesenchymal stromal cell engraftment and thus improving cell therapy of the infarcted myocardium. PMID: 28754835
    3. CT-1 mRNA levels in adipose tissue showed significant circadian fluctuations in young WT mice. Clock genes displayed a circadian rhythm in adipose tissue of both wild-type (WT) and CT-1-/- mice. However, the pattern was altered in CT-1-/- mice toward a lower percentage of the rhythm or lower amplitude, especially for Bmal1 and Clock. PMID: 28096235
    4. Cardiotrophin-1 modulates the production of adipokines in vitro and in vivo, suggesting that the regulation of the secretory function of adipocytes could be involved in the metabolic actions of this cytokine. PMID: 27608275
    5. Nuclear translocation of CT-1 regulates cardiomyogenesis of ES cells and involves calcium, NO, ROS as well as CT-1 regulated signaling pathways. PMID: 26005169
    6. Data suggest that Ctf1 up-regulates lipolysis in white adipocytes via 1) induction of perilipin, 2) activation of hormone sensitive lipase (via phosphorylation by PKA), and 3) inactivation of adipose triglyceride lipase (via up-regulation of G0S2). PMID: 25351614
    7. Cardiotrophin-1 (CT-1) is a hepatoprotective cytokine that modulates fat and glucose metabolism. Here we analyzed the changes in hepatic fat stores induced by recombinant CT-1 and its therapeutic potential in non-alcoholic fatty liver disease. PMID: 24362075
    8. The transgenic expression of CTF1 brought about a marked improvement on cognitive functioning in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease. PMID: 23541490
    9. CT-1 improves beta cell function and survival, and protects mice against STZ-induced diabetes PMID: 23358882
    10. CT-1 may be a major regulator of arterial stiffness with a major impact on the aging process. PMID: 23172930
    11. Hypoxia increased cardiotrophin-1 levels in cardiac cells through a direct regulation of CT-1 promoter by HIF-1alpha, protecting cells from apoptosis. PMID: 21771897
    12. Data suggest a key role for CT-1 in cardiac remodeling induced by aldosterone independent of changes in blood pressure levels. PMID: 21926338
    13. We conclude that CT-1 is a master regulator of fat and glucose metabolism with potential applications for treatment of obesity and insulin resistance. PMID: 21803294
    14. Treatment of embryoid bodies grown from pluripotent murine embryonic stem (ES) cells with cardiotrophin 1 significantly stimulated cardiomyogenesis and increased nuclear expression of the proliferation marker Ki-67. PMID: 15023522
    15. The embryonic neurons of mice regulate the onset of cortical gliogenesis via cardiotrophin-1. PMID: 16242406
    16. In embryonic deficient mice, preganglionic sympathetic neurons were reduced. PMID: 16467531
    17. Induction of interleukin-6 mRNA after infarct was significantly abrogated in CT-1 null mice compared to wild-type mice PMID: 17150369
    18. CT-1 is an essential endogenous defense of the liver against ischemia-reperfusion injury and is a key mediator of the protective effect induced by ischemic preconditioning. PMID: 17178916
    19. Our data show that CT-1 is a natural defense of the liver against apoptosis. This cytokine may have therapeutic potential. PMID: 17326158
    20. adipose tissue can be recognized as a source of CT-1, which could account for the high circulating levels of CT-1 in patients with metabolic syndrome X PMID: 17940213
    21. aldosterone induces CT-1 expression in adult HL-1 cardiomyocytes via genomic and nongenomic mechanisms PMID: 18566129
    22. Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling PMID: 18665789

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    IL-6 superfamily
  • 組織特異性：
    Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.
  • 數據庫鏈接：


主站蜘蛛池模板： 97视频在线观看播放| 日本边添边摸边做边爱| 少妇性饥渴无码a区免费| 狠狠躁夜夜躁人人爽蜜桃| 国产在线午夜不卡精品影院| 青草国产精品久久久久久| 色欲香天天天综合网站| 日韩人妻熟女中文字幕a美景之屋| 在线观看日本亚洲一区| 亚洲中字幕日产av片在线| 大陆极品少妇内射aaaaa| 日韩成人无码中文字幕| 98色婷婷在线| 乌克兰美女浓毛bbw| 国产热re99久久6国产精品首页| 欧美人与动牲交a欧美精品| 欧美交a欧美精品喷水| 无码av中文一区二区三区| 国产精品原创av片国产日韩| 国产suv精品一区二区五| 国产精品一区二区av蜜芽| 国产欧美丝袜在线二区| 搡老女人老妇女老熟妇| 最近在线更新8中文字幕免费| 国产成人精品日本亚洲| 日韩不卡1卡2卡三卡网站| 国产成人一区二区三区在线| 国产亚洲精品aaaaaaa片| 午夜内射中出视频| 无码精品人妻一区二区三区湄公河| 亚洲熟悉妇女xxx妇女av| 久久久欧美精品激情| 又粗又黄又爽视频免费看| 夜夜躁日日躁狠狠久久av| 国产精品制服| 人妻无码系列一区二区三区| 肉色欧美久久久久久久免费看| 午夜精品久久久久久久久久久久 | 日本高清www无色夜在线视频| 无码人妻av免费一区二区三区| 国产99在线 | 亚洲|