在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Calpain small subunit 1 (Capns1)

Recombinant Mouse Calpain small subunit 1 (Capns1)

  • 中文名稱：
    Recombinant Mouse Calpain small subunit 1(Capns1)
  • 貨號：
    CSB-YP004503MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Calpain small subunit 1(Capns1)
  • 貨號：
    CSB-EP004503MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Calpain small subunit 1(Capns1)
  • 貨號：
    CSB-EP004503MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Calpain small subunit 1(Capns1)
  • 貨號：
    CSB-BP004503MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Calpain small subunit 1(Capns1)
  • 貨號：
    CSB-MP004503MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Capns1
  • Uniprot No.：
  • 別名：
    Capns1; Capn4Calpain small subunit 1; CSS1; Calcium-activated neutral proteinase small subunit; CANP small subunit; Calcium-dependent protease small subunit; CDPS; Calcium-dependent protease small subunit 1; Calpain regulatory subunit
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-269
  • 氨基酸序列
    MFLVNSFLKG GGGGGGGGGL GGGLGNVLGG LISGAAGGGG GGGGGGMGLG GGGGGGGTAM RILGGVISAI SEAAAQYNPE PPPPRSHYSN IEANESEEVR QFRKLFVQLA GDDMEVSATE LMNILNKVVT RHPDLKTDGF GIDTCRSMVA VMDSDTTGKL GFEEFKYLWN NIKKWQAIYK RFDTDRSGTI GSHELPGAFE AAGFHLNEHL YSMIIRRYAD ESGNMDFDNF ISCLVRLDAM FRAFKSLDKN GTGQIQVNIQ EWLQLTMYS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • 基因功能參考文獻：
    1. Mitochondrial calpain-1 disrupts ATP synthase, leading to mitochondrial reactive oxygen species generation, which promotes proinflammatory response and myocardial dysfunction during endotoxemia. PMID: 26246018
    2. Calpain in osteoblasts regulates cell proliferation through its regulation of p27Kip1. Osteoblast-specific capns1 knockout mice developed a high-fat diet-induced excess body weight gain and impaired glucose tolerance. PMID: 22821549
    3. effects of Capn4 deletion may be mediated through prevention of IkappaB degradation and NF-kappaB activation, resulting in inhibition of inflammatory responses. PMID: 22753411
    4. Calpain 4 is essential for the tyrosine phosphorylation of galectin-3, and its ultimate secretion from the cell, and its secretion probably interferes with the production of traction forces. PMID: 21640083
    5. osteoblast-specific Capns1 knockout mice with osteoporosis and reduced bone resorptive function, exhibited reduced serum uncarboxylated osteocalcin levels and a lean phenotype under a normal chow diet. PMID: 21569760
    6. Calpain 4 is not necessary for LFA-1-mediated adhesion, conjugation or migration. PMID: 20479866
    7. Data suggest that the calpain small subunit, Capn4, is essential for proper chondrocyte functions in embryonic growth plates. PMID: 20368361
    8. calpain-mediated endoproteolytic cleavage of PrP(Sc) may be an important event in prion propagation PMID: 15026410
    9. In calpain-deficient cells, autophagy is impaired with a resulting dramatic increase in apoptotic cell death. PMID: 17101693
    10. results suggest a regulatory connection between calpain and RhoGDI-1 in promoting formation of membrane blebs PMID: 18076376
    11. Capn4 in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation PMID: 18515801
    12. CAPNS1 interferes with PP2A-Akt interaction consequently affecting FoxO3A-dependent cell death. PMID: 19029949
    13. Capn4 overexpression underlies invasion and metastasis after liver transplantation for hepatocellular carcinoma and may be a candidate biomarker for future diagnosis and a target for therapy. PMID: 19053044

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 色多多性虎精品无码av| 国产在线精品一区二区三区 | 久久精品aⅴ无码中文字字幕蜜桃| 国产手机在线精品| 亚洲欧美日韩久久一区二区| 天堂а√中文在线| 顶级少妇做爰视频在线观看| 乱子伦一区二区三区| 四虎永久在线精品免费视频观看 | 女人被爽到高潮视频免费国产| 国产波霸爆乳一区二区| 三级4级全黄60分钟| 国产精品亚洲综合一区在线观看| 日本熟妇hdsex视频| 少妇高潮喷水惨叫久久久久电影| 国产精品特级露脸av毛片| 亚洲中文字幕久在线| 亚洲偷精品国产五月丁香麻豆| 欧美性受xxxx狂喷水| 亚洲日韩一页精品发布| 欧美激情一区二区成人| 国产台湾无码av片在线观看 | 国产精品www夜色视频| 亚洲精品国产综合麻豆久久99| 99精品全国免费观看视频| 青青草原综合久久大伊人| 国产成a人亚洲精v品无码| 亚洲欧洲国产综合aⅴ无码| 亚洲中文字幕无码av在线| 2020无码专区人妻系列日韩| 蜜桃av久久久一区二区三区麻豆| 国产av亚洲精品久久久久久小说| 天美传媒一区二区| 国产拍拍拍无码视频免费| 国内精品无码一区二区三区| 精品综合久久久久久98| 人妻教师痴汉电车波多野结衣| 午夜成人影院网站18进| 熟女少妇丰满一区二区| 国模少妇一区二区三区| 尤物色综合欧美五月俺也去 |