在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse COP9 signalosome complex subunit 6 (Cops6)

Recombinant Mouse COP9 signalosome complex subunit 6 (Cops6)

  • 中文名稱：
    Recombinant Mouse COP9 signalosome complex subunit 6(Cops6)
  • 貨號：
    CSB-YP005793MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse COP9 signalosome complex subunit 6(Cops6)
  • 貨號：
    CSB-EP005793MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse COP9 signalosome complex subunit 6(Cops6)
  • 貨號：
    CSB-EP005793MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse COP9 signalosome complex subunit 6(Cops6)
  • 貨號：
    CSB-BP005793MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse COP9 signalosome complex subunit 6(Cops6)
  • 貨號：
    CSB-MP005793MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Cops6
  • Uniprot No.：
  • 別名：
    Cops6; Csn6COP9 signalosome complex subunit 6; SGN6; Signalosome subunit 6; JAB1-containing signalosome subunit 6
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-324
  • 氨基酸序列
    MAAAAAAGAN GSGGSSGMEV DAAVPSVMAS GVTGSVSVAL HPLVILNISD HWIRMRSQEG RPMQVIGALI GKQEGRNIEV MNSFELLSHT VEEKIIIDKE YYYTKEEQFK QVFKELEFLG WYTTGGPPDP SDIHVHKQVC EIIESPLFLK LNPMTKHTDL PVSVFESVID IINGEATMLF AELTYTLATE EAERIGVDHV ARMTATGSGE NSTVAEHLIA QHSAIKMLHS RVKLILEYVK ASEAGEVPFN HEILREAYAL CHCLPVLSTD KFKTDFYDQC NDVGLMAYLG TITKTCNTMN QFVNKFNVLY DRQGIGRRMR GLFF
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity. Stabilizes COP1 through reducing COP1 auto-ubiquitination and decelerating COP1 turnover rate, hence regulates the ubiquitination of COP1 targets, including SFN.
  • 基因功能參考文獻：
    1. CSN6 and Rab34 are involved in AR trafficking by regulating the phosphorylation signaling pathway. These findings provide new insights into the testosterone signaling pathway in Sertoli cells that mediates spermatogenesis. PMID: 29991022
    2. results define a mechanism for the regulation of Myc stability through the CSN-Cullin-Fbxw7 axis and provide insights into the correlation of CSN6 overexpression with Myc stabilization/activation during tumorigenesis PMID: 25395170
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase M67A family, CSN6 subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 太粗太深了太紧太爽了动态图男男| 1000部啪啪未满十八勿入下载| 熟妇人妻无码中文字幕老熟妇| 国产蝌蚪视频一区二区三区 | 亚洲加勒比无码一区二区| 久久久久女教师免费一区| 国产精品欧美福利久久| 性xxxxx欧美极品少妇| 天天综合爱天天综合色| 精品无人区无码乱码毛片国产| 亚洲综合av永久无码精品一区二区 | 亚洲vav在线男人的天堂| av免费播放一区二区三区| 日本xxxx裸体xxxx视频大全| 亚洲欧美在线观看| 三级视频兔费看| 尹人香蕉久久99天天拍欧美p7| 国产成人a在线观看视频| 精品亚洲欧美无人区乱码| 亚洲伊人色欲综合网| 国产av国内精品jk制服| 国产福利无码一区在线| 久久久久久无码午夜精品直播| 香港三级精品三级在线专区| 中文人妻无码一区二区三区信息| 七七久久成人影院网站| 乱色国内精品视频在线| 中文字幕一区二区三区乱码| 午夜精品久久久久久中宇| 色伊人亚洲综合网站| 一区二区三区国产精华液| 国产黑色丝袜在线视频| 亚洲性无码av中文字幕| 久久久噜噜噜久久熟女| 亚洲日本成本人观看| 窝窝影院午夜看片| 伊人婷婷色香五月综合缴缴情| 曰本女人牲交高潮视频| 国产成人无码av一区二区在线观看 | 精品一区二区三区免费毛片爱| 7777精品久久久大香线蕉|