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  4. Recombinant Mouse CMRF35-like molecule 8 (Cd300a), partial

Recombinant Mouse CMRF35-like molecule 8 (Cd300a), partial

  • 中文名稱：
    Recombinant Mouse CMRF35-like molecule 8(Cd300a),partial
  • 貨號：
    CSB-YP747575MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse CMRF35-like molecule 8(Cd300a),partial
  • 貨號：
    CSB-EP747575MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse CMRF35-like molecule 8(Cd300a),partial
  • 貨號：
    CSB-EP747575MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse CMRF35-like molecule 8(Cd300a),partial
  • 貨號：
    CSB-BP747575MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse CMRF35-like molecule 8(Cd300a),partial
  • 貨號：
    CSB-MP747575MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cd300a; Clm8; Lmir1; Mcpir1CMRF35-like molecule 8; CLM-8; CD300 antigen-like family member A; Leukocyte mono-Ig-like receptor 1; Mast cell-derived paired immunoglobulin-like receptor 1; Myeloid-associated immunoglobulin-like receptor 1; MAIR-1; MAIR-I; CD antigen CD300a
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
  • 基因功能參考文獻：
    1. The results indicate that CD300a on MCs and DCs regulates neutrophil recruitment into the peritoneal cavity after cecal ligation and puncture (CLP). PMID: 27836913
    2. Epithelial apoptotic cells negatively regulated commensal-mediated signaling in dendritic cells via CD300a for Treg cell proliferation. PMID: 26855029
    3. Data show that peroxisome proliferator activator receptor delta (PPARdelta/beta) directly regulates CD300a protein in macrophages. PMID: 24958459
    4. These results suggest that CD300a is involved in aluminium-induced Th2 skewing. PMID: 25911756
    5. study demonstrates a new tumor immune evasion mechanism that is mediated through the interaction between phosphatidylserine and CD300a and we suggest that CD300c, similarly to CD300a, also interacts with phosphatidylserine. PMID: 23640773
    6. CD300a-deficient mice showed increased neutrophil recruitment and improved bacterial clearance in the peritoneal cavity. PMID: 22826299
    7. These results indicated that CD300a is a new phosphatidylserine receptor. PMID: 22185693
    8. in a murine model of allergic peritonitis, neutralization of the murine homolog of IRp60, LMIR1, led to a significantly augmented release of inflammatory mediators and eosinophilic infiltration. PMID: 16339535

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  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    CD300 family
  • 組織特異性：
    Present on the surface of the majority of myeloid cells and a subset of B-cells. Present on the surface of NK cells after IL-12 stimulation.
  • 數據庫鏈接：


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