Recombinant Mouse C-Jun-amino-terminal kinase-interacting protein 2 (Mapk8ip2), partial

中文名稱：

小鼠Mapk8ip2重組蛋白
貨號：

CSB-YP884143MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Mapk8ip2重組蛋白
貨號：

CSB-EP884143MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Mapk8ip2重組蛋白
貨號：

CSB-EP884143MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Mapk8ip2重組蛋白
貨號：

CSB-BP884143MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Mapk8ip2重組蛋白
貨號：

CSB-MP884143MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Mapk8ip2
Uniprot No.：

Q9ERE9
別名：

Mapk8ip2; Ib2; Jip2; C-Jun-amino-terminal kinase-interacting protein 2; JIP-2; JNK-interacting protein 2; Islet-brain-2; IB-2; JNK MAP kinase scaffold protein 2; Mitogen-activated protein kinase 8-interacting protein 2
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells.
基因功能參考文獻：
1. JIP2 does not influence the processing of APP, although it is known that both JIP1b and JIP2 equally regulate the JNK signaling cascade PMID: 12023290
2. there is a signaling module in which IB2 scaffolds a MLK3/MKK/p38delta kinase cascade. PMID: 12244047
3. JIP scaffold proteins are critically required for normal NMDA receptor function. PMID: 17875667
4. Data demonstrate that JIP-2 and -2 proteins can influence insulin-stimulated signal transduction mediated by insulin receptor substrate proteins. PMID: 19564410
亞細胞定位：

Cytoplasm.
蛋白家族：

JIP scaffold family
組織特異性：

Highly expressed in brain. Expressed in all neurons. Also expressed in testis, primarily in the epididymal epidermis.
數據庫鏈接：

KEGG: mmu:60597

STRING: 10090.ENSMUSP00000023291

UniGene: Mm.173337