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Recombinant Mouse Aryl-hydrocarbon-interacting protein-like 1 (Aipl1)

  • 中文名稱:
    Recombinant Mouse Aryl-hydrocarbon-interacting protein-like 1(Aipl1)
  • 貨號(hào):
    CSB-YP842121MO
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Aryl-hydrocarbon-interacting protein-like 1(Aipl1)
  • 貨號(hào):
    CSB-EP842121MO
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse Aryl-hydrocarbon-interacting protein-like 1(Aipl1)
  • 貨號(hào):
    CSB-EP842121MO-B
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Aryl-hydrocarbon-interacting protein-like 1(Aipl1)
  • 貨號(hào):
    CSB-BP842121MO
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse Aryl-hydrocarbon-interacting protein-like 1(Aipl1)
  • 貨號(hào):
    CSB-MP842121MO
  • 說(shuō)明書:
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Aipl1
  • Uniprot No.:
  • 別名:
    Aipl1; Aryl-hydrocarbon-interacting protein-like 1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-328
  • 氨基酸序列
    MDVSLLLNVE GVKKTILHGG TGELPSFITG SRVTFHFRTM KCDDERTVID DSKQVGQPMS IIIGNMFKLE VWETLLTSMR LGEVAEFWCD TIHTGVYPML SRSLRQVAEG KDPTSWHVHT CGLANMFAYH TLGYEDLDEL QKEPQPLVFL IELLQVEAPN EYQRETWNLN NEERMQAVPL LHGEGNRLYK LGRYDQAATK YQEAIVCLRN LQTKEKPWEV EWLKLEKMIN TLILNYCQCL LKKEEYYEVL EHTSDILRHH PGIVKAYYMR ARAHAEVWNA EEAKADLEKV LELEPSMRKA VLRELRLLES RLADKQEEER QRCRSMLG
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May be important in protein trafficking and/or protein folding and stabilization.
  • 基因功能參考文獻(xiàn):
    1. mechanistic differences behind the death of rods and cones in retinal degenerative disease caused by deficiencies in AIPL1. PMID: 24108108
    2. In this chapter, using results obtained from multiple lines of animal models, we discuss the role for AIPL1 in photoreceptors. PMID: 24664679
    3. The binding of PDE6A farnesyl is essential to normal function of AIPL1 and its disruption is one of the mechanisms underlying Leber congenital amaurosis. PMID: 23737531
    4. Loss of AIPL1 would result in a condition that phenocopies retinal degenerations in the rd mouse and in a subgroup of human PMID: 15365173
    5. AIPL1 enhances the stability of phosphodiesterase and is essential for photoreceptor viability. PMID: 15365178
    6. AIPL1 has a role in the retina and in mouse models of Leber congenital amaurosis [review] PMID: 17249560
    7. AIPL1 interacts with the catalytic subunit (alpha) of PDE6 and is needed for the assembly of functional rod PDE6 subunits. PMID: 19758987

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  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus.
  • 數(shù)據(jù)庫(kù)鏈接:


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