在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Anterior gradient protein 2 homolog (Agr2)

  • 中文名稱:
    Recombinant Mouse Anterior gradient protein 2 homolog(Agr2)
  • 貨號:
    CSB-YP001458MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Anterior gradient protein 2 homolog(Agr2)
  • 貨號:
    CSB-EP001458MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Anterior gradient protein 2 homolog(Agr2)
  • 貨號:
    CSB-MP001458MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Agr2
  • Uniprot No.:
  • 別名:
    Agr2; Gob4Anterior gradient protein 2 homolog; AG-2; mAG-2; Protein Gob-4; Secreted cement gland protein XAG-2 homolog
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區(qū)域:
    21-175
  • 氨基酸序列
    KDTTVKSGAK KDPKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYRSKTSNR PLMVIHHLDE CPHSQALKKV FAEHKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIVF VDPSLTVRAD ITGRYSNRLY AYEPSDTALL YDNMKKALKL LKTEL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion.
  • 基因功能參考文獻:
    1. AGR2 accelerates skin wound healing through regulation of cell migration. PMID: 28665039
    2. AGR2 induced in ER-stressed and inflammatory pre-neoplastic pancreas is a potential marker of cancer progenitor cells with an important functional role in PDAC initiation. PMID: 27941872
    3. impact of AGR2 expression and EGFR signaling on tissue regeneration PMID: 27764193
    4. EGFR-mediated signaling in NCI-H460 cells is disrupted with reduced AGR2 expression. PMID: 25666625
    5. AGR2 has both intracellular and extracellular effects in the intestine PMID: 25111734
    6. Results indicate that DNA methylation within the AGR2 promoter modulates more aggressive cancer cell phenotypes. PMID: 24920423
    7. It was concluded that: the expression of AGR2 protein was significantly higher in asthmatic mice as compared with their normal counterparts; the expression was obviously related to the expression of Muc5ac protein and IL-13. PMID: 23392704
    8. Agr2 consequently serves to maintain the balance between proliferating and differentiated epithelial cells. PMID: 23209296
    9. Agr2 facilitates normal lobuloalveolar development by regulating mammary epithelial cell proliferation; we found no effects on apoptosis in Agr2(-/-) mammary epithelial cells. PMID: 22819674
    10. Loss of Foxp1/4 in the developing lung and in postnatal secretory epithelium leads to ectopic activation of the goblet cell fate program, in part, through de-repression of the protein disulfide isomerase anterior gradient 2 (Agr2). PMID: 22675208
    11. studies implicate Agr2 in intestinal homeostasis and ER stress and suggest a role in the etiology of inflammatory bowel disease PMID: 20025862
    12. AGR2 may be important for the growth and development of the intestine as well as esophageal adenocarcinomas. PMID: 18199544
    13. Overexpression of Agr2 is associated with asthma. PMID: 19028979
    14. AGR2 is a unique member of the protein disulfide isomerase family, with a specialized and nonredundant role in intestinal mucus production PMID: 19359471

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted. Endoplasmic reticulum.
  • 蛋白家族:
    AGR family
  • 組織特異性:
    Expressed in lung, skeletal muscle, testis, liver, stomach, colon, small intestine, the goblet cells of the intestine and the mucuous neck cells of the stomach.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 国产成人国拍亚洲精品| 无码av无码天堂资源网影音先锋| 亚洲一区二区三区波多野结衣| 精品无码成人久久久久久| 亚洲中文字幕无码永久在线不卡| 色狠狠av老熟女| 久久人搡人人玩人妻精品首页| av无码小缝喷白浆在线观看| 一个色综合国产色综合| 日本高清在线天码一区播放| 中文字幕人妻偷伦在线视频| 五十路熟女一区二区三区| 性高湖久久久久久久久aaaaa| 色老久久精品偷偷鲁| 久久香蕉综合色一综合色88| 六月丁香亚洲综合在线视频| 日韩亚洲国产高清免费视频| 熟女肥臀白浆大屁股一区二区 | 亚洲综合久久成人a片| 东北老女人高潮大叫对白| 亚洲日韩aⅴ在线视频| 黑人粗长大战亚洲女| 香港经典a毛片免费观看hd| 亚洲国产成人精品无码一区二区| 国内久久婷婷六月综合欲色啪| 搡女人真爽免费视频大全| 国产97在线 | 中文| 中文午夜乱理片无码| 国产亚洲精品自在久久蜜tv| 精品人无码一区二区三区| 女人高潮内射99精品| www片香蕉内射在线88av8| 午夜福利无遮挡十八禁视频| 污污网站18禁在线永久免费观看| 国产精品无码久久综合| 久久人人爽人人爽人人片| 色老头av亚洲一区二区男男| 美女又大又黄www免费网站| 国产草草影院ccyycom| 一区二区亚洲精品国产精华液| 熟女毛多熟妇人妻在线视频|