在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Angiomotin (Amot), partial

Recombinant Mouse Angiomotin (Amot), partial

  • 中文名稱：
    Recombinant Mouse Angiomotin(Amot) ,partial
  • 貨號：
    CSB-YP001677MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Angiomotin(Amot) ,partial
  • 貨號：
    CSB-EP001677MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Angiomotin(Amot) ,partial
  • 貨號：
    CSB-EP001677MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Angiomotin(Amot) ,partial
  • 貨號：
    CSB-BP001677MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Angiomotin(Amot) ,partial
  • 貨號：
    CSB-MP001677MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Amot; Kiaa1071Angiomotin
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
  • 基因功能參考文獻(xiàn)：
    1. Rho attenuates the interaction between Amot and Nf2 by binding to the coiled-coil domain of Amot. PMID: 28947533
    2. a new function of RNF146 and tankyrase in stabilizing the Crumbs complex through downregulation of AMOT proteins at the apical membrane, is reported. PMID: 27521426
    3. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer. PMID: 25381822
    4. The loss of Angiomotin, together with Angiomotin-like 2, leads to differentiation of inner cell mass cells and compromised peri-implantation development. PMID: 23903990
    5. The phosphorylation of S176 in the N-terminal domain of Amot is a critical step for activation of the Hippo pathway in adherens junctions and cell polarity disconnects the Hippo pathway from cell-cell adhesion by sequestering Amot from AJs. PMID: 23791731
    6. Amot, Amotl1, and Amotl2 are differentially expressed in uterine cells during the peri-implantation period. PMID: 22813598
    7. A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors. PMID: 22426512
    8. Depletion of Angiomotin in Nf2(-/-) Schwann cells attenuates the Ras-MAPK signaling pathway, impedes cellular proliferation in vitro and tumorigenesis in vivo PMID: 21481793
    9. Angiomotin may promote neoplastic angiogenesis by both stimulating invasion as well as stabilizing established tubes. PMID: 14730344
    10. angiomotin, in addition to controlling cell motility, may play a role in the assembly of endothelial cell-cell junctions PMID: 16043488
    11. p80- and p130-angiomotin play coordinating roles in vascular tube formation by affecting cell migration and cell shape, respectively. PMID: 16640563
    12. Data show that MUPP1 interacts with angiomotin (Amot), JEAP/Amot-like 1 and MASCOT/Amot-like 2, and that all the Amot/JEAP family proteins also interacted with Patj, a close relative of MUPP1. PMID: 17397395
    13. 75% of Amot knockout mice die between embryonic day 11 (E11) and E11.5 and exhibit severe vascular insufficiency in the intersomitic region as well as dilated vessels in the brain. PMID: 17699752
    14. Homo-oligomerization of p80-Amot and hetero-oligomerization of both isoforms are critical for a switch between a migratory and a non-migratory cell phenotype in endothelial cells. PMID: 18164266
    15. Amot and AmotL1 have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 affects the stability of cell-cell junctions. PMID: 19590046

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell junction, tight junction.
  • 蛋白家族：
    Angiomotin family
  • 組織特異性：
    Expressed in brain, skeletal muscle and placenta.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产精品成人3p一区二区三区| 最近中文字幕在线中文视频| 日韩成人无码一区二区三区| 国产精品爆乳在线播放第一人称| 亚洲一区在线日韩在线秋葵| 国产亚洲精品97在线视频一| 久久精品av麻豆| 国产午精品午夜福利757视频播放| 久久天天躁狠狠躁夜夜2019| 玩两个丰满老熟女| 国产大屁股喷水视频在线观看| 人妻夜夜爽天天爽三区麻豆av网站| 色婷婷六月亚洲婷婷丁香| 日本亚洲欧美日韩国产ay| 国产午夜福利不卡在线秋霞秋霞| 国产精品久久久久久久久久妞妞| 国产特级毛片aaaaaa高潮流水| 真人做人试看60分钟免费| 国产成人av免费网址| 人妻无码少妇一区二区| 日日噜狠狠噜天天噜av| 中文字幕乱码人妻综合二区三区| 波多野42部无码喷潮| 久久婷婷五月综合色欧美蜜芽| 在线无码av一区二区三区| 国产做爰xxxⅹ久久久精华液| 伊人久久大香线蕉综合网站| 亚洲中文字幕无码av永久| 欧美激情精品成人一区| 日韩亚洲国产高清免费视频| 久久综合九色综合网站| 欲香欲色天天天综合和网| 日本道免费精品一区二区| 国产在线观看免费人成视频| 又大又粗弄得我出好多水| 日本道色综合久久影院| 日产精品卡1卡2卡三卡在线| 欧美成 人 网 站 免费| 欧洲精品码一区二区三区免费看 | 国产成人亚洲精品另类动态| 特级毛片全部免费播放|