在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Agouti-signaling protein (Asip)

Recombinant Mouse Agouti-signaling protein (Asip)

  • 中文名稱：
    Recombinant Mouse Agouti-signaling protein(Asip)
  • 貨號：
    CSB-YP002212MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Agouti-signaling protein(Asip)
  • 貨號：
    CSB-EP002212MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Agouti-signaling protein(Asip)
  • 貨號：
    CSB-EP002212MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Agouti-signaling protein(Asip)
  • 貨號：
    CSB-BP002212MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Agouti-signaling protein(Asip)
  • 貨號：
    CSB-MP002212MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Asip; aAgouti-signaling protein; ASP; Agouti coat color protein; Agouti switch protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    23-131
  • 氨基酸序列
    HLALEETL GDDRSLRSNS SMNSLDFSSV SIVALNKKSK KISRKEAEKR KRSSKKKASM KKVARPPPPS PCVATRDSCK PPAPACCDPC ASCQCRFFGS ACTCRVLNPN C
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). Causes hair follicle melanocytes to synthesize phaeomelanin instead of black or brown pigment eumelanin and produces hairs with a subapical yellow band on an otherwise black or brown background when expressed during the mid-portion of hair growth.
  • 基因功能參考文獻：
    1. The data confirm development of obesity and disturbance of lipid metabolism in Ay males. There were no changes in testicular function. PMID: 30188668
    2. Methylation analysis reveals that although most lines display normal methylation at IAP elements in general, the Avy IAP element is essentially unmethylated. PMID: 25191835
    3. observed variable histone patterns in the 5' long terminal repeat of the viable yellow agouti (A(vy)) metastable epiallele PMID: 20671424
    4. Data suggest that that the agouti/melanocortin signaling pathway regulates levels of peroxisome proliferator activated receptor gamma in adipocytes. PMID: 12851309
    5. AP overproduction increased the response of the pituitary adrenal system to short-restraint stress due to increased adrenal responsiveness to ACTH PMID: 15296483
    6. Local long-term mouse Agouti expression in the PVN, DMH, and LH differentially induced hyperphagia and accelerated body weight gain without apparent changes in central neuropeptide systems that are known to stimulate food intake in rats. PMID: 15537888
    7. mice with different agouti genotypes had identical basal corticosterone levels, though yellow mice, as compared with black mice, had increased corticosterone levels after restriction stress PMID: 15779332
    8. Corin plays a critical role in specifying coat color and acts downstream of agouti gene expression as a suppressor of the agouti pathway. PMID: 18057101
    9. The preimplantation embryo's growth environment can affect the postnatal expression of a defined epigenetically sensitive allele. PMID: 18562706
    10. pigment-related genes targeted by ASP and by alphaMSH PMID: 19174519
    11. study shows ASIP-MC1R signaling includes a cAMP-independent pathway through attractin and mahogunin, while the known cAMP-dependent component requires neither attractin nor mahogunin PMID: 19493315
    12. effects of the A(y) allele on mandible morphology on different strain backgrounds, DDD and B6 PMID: 19644225

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 組織特異性：
    Epithelial cells of the hair follicles and the epidermis.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲成年轻人电影网站www| 草草久久97超级碰碰碰| 亚洲国产精品久久久久秋霞小说| 亚洲一区在线观看尤物| 国产成人精品一区二区三区视频 | 亚洲国产高清在线一区二区三区| 色视频无码专区在线观看| 熟女乱亚洲图| 爽爽影院免费观看视频| 亚洲一卡一卡二新区无人区| 黑人强伦姧人妻久久| 国产精品亚洲欧美中字| 国产毛片欧美毛片久久久| 国产熟妇高潮呻吟喷水| 亚洲一卡一卡二新区迎热烈讨论 | 国产精品嫩草99av在线| 特级西西人体444www高清大胆 | 久久人人爽人人爽人人片av高清 | 又黄又湿免费高清视频| 亚洲人成色77777| 麻豆精品国产精华精华液好用吗| 成人午夜电影福利免费| 最新中文乱码字字幕在线| 亚洲精品色情app在线下载观看| 国产三级av在线播放| 国产在线 | 欧洲| 国产三级精品三级在线专1| 欧美性色黄大片| 亚洲精品久久久久久| 热久久99这里有精品综合久久| 国产成人综合久久精品| 丁香五香天堂网| 亚洲精品久久久久久久观小说| 女高中生自慰污污网站| 日本少妇高潮喷水xxxxxxx| 精品性高朝久久久久久久| 亚洲欧美综合精品久久成人网| 精品人妻人人做人人爽夜夜爽 | 日本免费一本一二区三区| av东京热无码专区| 欧美gv在线观看|