在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Adrenocortical dysplasia protein (Acd)

  • 中文名稱:
    Recombinant Mouse Adrenocortical dysplasia protein(Acd)
  • 貨號:
    CSB-YP682726MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse Adrenocortical dysplasia protein(Acd)
  • 貨號:
    CSB-EP682726MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse Adrenocortical dysplasia protein(Acd)
  • 貨號:
    CSB-EP682726MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse Adrenocortical dysplasia protein(Acd)
  • 貨號:
    CSB-BP682726MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse Adrenocortical dysplasia protein(Acd)
  • 貨號:
    CSB-MP682726MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    AcdAdrenocortical dysplasia protein
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-416
  • 氨基酸序列
    MSDSGLLALQ PWIRELILGS ETLSSPRTGQ LLKVLQDSET PGPSSAPDTP DTGAVLLVSD GTHSVRCVVT RNAIDTSDWE EKELGFRGTE GRLLLLQACG LRVQVAQDHA PAEFYLQVDR FNLLPTEQPR IQVTGCNQDS DVQRKLNECL EDHLSESASS SAGLTLSQLL DEVREDQDHR GALVCLAKSC LVLKGPCTTT PLTDWITSGS QALGKAVFTV SGSLLHIPEG EEQILSSTGS SQKARGTSAS PSHMPLEESG ASVSLLSALA TSDPGQMDSS QSPPAVGSTS PRAQAPTSPP CNSTPSSLLL NCSPSLSPLH PAPRSHQSCE TRAQAPKLEF QCSFKKRQLL PRTSAQELCS VWEPPERHRD TSAFQYKYET PSASLHTQVQ TARLSPQLVA WALNIVMESE SELTQV
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
  • 基因功能參考文獻:
    1. Analyses demonstrate that the majority of differentially expressed genes in acd mutant embryos are due to p53-dependent mechanisms and reflect the observed phenotypic differences between acd mutant and double mutant embryos. PMID: 30189268
    2. Mouse hematopoietic stem cells are acutely sensitive to inactivation of the shelterin gene Acd. PMID: 24316971
    3. telomeric regulator is required for proper urogenital ridge differentiation, axial skeleton specification and limb patterning in mice. PMID: 15537664
    4. Tumors from Acd(acd/acd) p53(+/-) mice show a striking switch from the classic spectrum of p53(-/-) mice toward carcinomas. PMID: 19477426
  • 相關疾病:
    Defects in Acd are the cause of adrenocortical dysplasia (ACD). ACD is a spontaneous autosomal recessive mouse mutant resulting from spontaneous splicing mutation of acd. ACD mice are characterized by developmental defects in organs derived from the urogenital ridge, reduced survival, poor growth, skin hyperpigmentation and adrenal insufficiency. Forty percent of the mutants died within 24 hours. Analysis of E14.5 to E17.5 embryos revealed reduced formation of caudal structure as well as limb defects.
  • 亞細胞定位:
    Nucleus. Chromosome, telomere.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲色成人四虎在线观看| 中文字幕人妻第一区| 色婷婷狠狠97成为人免费| 国产精品亚洲二区在线看| 久久久久久久久久久综合日本| 免费人成视频在线观看网站| 忍不住的亲子中文字幕| 国产又色又爽无遮挡免费| 亚洲综合无码中文字幕第2页| 亚洲另类欧美在线电影| 国内精品久久久久影院亚瑟| 国产东北肥熟老胖女| 播放男人添女人下边视频| 内射人妻无套中出无码| 日本精品αv中文字幕| 国产超碰女人任你爽| 精品无码久久久久国产| 免费无遮挡无码永久在线观看视频| 欧美疯狂性受xxxxx喷水| 84pao国产成视频永久免费| 成人麻豆亚洲综合无码精品| 国色天香社区在线视频| 亚洲国产精品久久久久久无码 | 加勒比久久综合网天天| 欧美性猛交xxxx免费视频软件| 亚洲狠狠成人网| 日韩av无码一区二区三区不卡毛片| 久久久橹橹橹久久久久| 自拍偷自拍亚洲精品播放| 久久精品黄aa片一区二区三区 | 国产高清成人免费视频在线观看| 亚洲综合小说另类图片五月天| 国产三级视频在线观看视| 亚洲精品黑牛一区二区三区| 色综合中文综合网| 国产成人免费97在线观看| 欧美日产国产新一区| 大胆日本熟妇xxxx| 日韩人妻无码一区二区三区| 欧美成人一区二区三区| 中文字幕+乱码+中文乱码www|