在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Adenylate cyclase type 10 (Adcy10), partial

In Stock
  • 中文名稱:
    Recombinant Mouse Adenylate cyclase type 10 (Adcy10), partial
  • 貨號(hào):
    CSB-EP804898MO
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    Germ cell soluble adenylyl cyclase;sAC;Testicular soluble adenylyl cyclase
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    58.9 kDa
  • 表達(dá)區(qū)域:
    1-470aa
  • 氨基酸序列
    MSARRQELQDRAIVKIAAHLPDLIVYGDFSPERPSVKCFDGVLMFVDISGFTAMTEKFSTAMYMDRGAEQLVEILNYYISAIVEKVLIFGGDILKFAGDALLALWKVERKQLKNIITVVIKCSLEIHGLFEAKEAEEGLDIRVKIGLAAGHITMLVFGDETRNYFLVIGQAVDDVRLAQNMAQMNDVILSPNCWQLCDRSMIEIERIPDQRAVKVSFLKPPPTFNFDEFFTKCMGFMDYYPSGDHKNFLRLACMLESDPELELSLQKYVMEIILKQIDDKQLRGYLSELRPVTIVFVNLMFKEQDKVEVIGSAIQAACVHITSVLKVFRGQINKVFMFDKGCSFLCVFGFPGEKAPDEITHALESAVDIFDFCSQVHKIRTVSIGVASGIVFCGIVGHTVRHEYTVIGQKVNIAARMMMYYPGIVSCDSVTYDGSNLPAYFFKELPKKVMKGVADPGPVYQCLGLNEKVM
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.
  • 基因功能參考文獻(xiàn):
    1. This study showed that sAC is essential for lysosomal acidification in addition to its other roles in cell physiology. PMID: 27670898
    2. sAC is a regulator of gene expression involved in aldosterone signaling and an important regulator of endothelial stiffness. PMID: 24420537
    3. cAMP pathways are compartmentalized in sperm, with Gs proteins and transmembrane adenyl cyclase in the head and Adcy10 and PKA in the flagellum. PMID: 24129574
    4. sAC is necessary for normal glucose-stimulated insulin secretion in vitro and in vivo. PMID: 24100033
    5. Regulation of anterior chamber drainage by bicarbonate-sensitive soluble adenylyl cyclase in the ciliary body. PMID: 21994938
    6. Soluble guanylyl cyclase expression is reduced in experimental asthma contributing to the observed airway hyperreactivity. PMID: 16143586
    7. The role of nitric oxide synthase 3 in the activation of soluble guanylyl cyclase in platelets is reported. PMID: 16144836
    8. Plays a critical role in cAMP signaling in spermatozoa; defective cAMP production prevents engagement of multiple components of capacitation resulting in male infertility. PMID: 16842770
    9. These results suggest that NO regulation of MMP-9 secreted from macrophages may occur chemically by reactive nitrogen species-mediated protein modification, biologically through soluble guanylyl-cyclase. PMID: 17942699
    10. External Ca2+ binds an unidentified extracellular protein that is required for HCO3(-) to engage cyclic AMP-mediated activation of motility. PMID: 17950270
    11. Soluble adenylyl cyclase is required for activation of sperm but does not have a direct effect on hyperactivation. PMID: 18255013

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Cell projection, cilium. Cytoplasm. Mitochondrion.
  • 蛋白家族:
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 組織特異性:
    Expressed in testis.
  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 国产精品久久无码不卡| 十八18禁国产精品www| 无码一区二区三区免费| 精品久久欧美熟妇www| 最新国产成人无码久久| 欧美人和黑人牲交网站上线| 对白脏话肉麻粗话av | 久久99精品国产自在现线小黄鸭| 中国少妇大p毛茸茸| 国产人成视频在线观看| 久久婷婷色综合一区二区| 国产精品原创巨作av女教师| 欧美老肥熟妇多毛xxxxx| 久久久久成人片免费观看蜜芽| 最新亚洲春色av无码专区| 国产激情久久久久影院小草| 国产农村乱子伦精品视频| 久久婷婷成人综合色综合| 秋霞国产午夜伦午夜福利片| 久久超碰97人人做人人爱| 亚洲精品久久久久中文字幕m男| 亚洲日韩久久综合中文字幕| 日韩免费特黄一二三区| 理论片午午伦夜理片影院| 国产成人一区二区三区app| 玩弄中年熟妇正在播放| 美女黄18以下禁止观看| 国内久久婷婷五月综合色| 玩弄丰满少妇人妻视频| 欧亚乱熟女一区二区在线| 亚洲成在人线av无码| 一本一本久久a久久综合精品| 影音先锋久久久久av综合网成人| 国产精品午夜福利视频234区| 精品国产一区二区三区麻豆| 色屁屁www影院免费观看| 成熟人妻av无码专区| 在线观看免费网页欧美成| 精品一卡2卡3卡4卡新区在线| 亚洲熟妇少妇任你躁在线观看无码| 狠狠色丁香久久婷婷综合五月 |