在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial (Acat1)

Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial (Acat1)

  • 中文名稱：
    Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial(Acat1)
  • 貨號：
    CSB-YP851236MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial(Acat1)
  • 貨號：
    CSB-EP851236MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial(Acat1)
  • 貨號：
    CSB-EP851236MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial(Acat1)
  • 貨號：
    CSB-BP851236MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Acetyl-CoA acetyltransferase, mitochondrial(Acat1)
  • 貨號：
    CSB-MP851236MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Acat1
  • Uniprot No.：
  • 別名：
    Acat1; Acetyl-CoA acetyltransferase; mitochondrial; EC 2.3.1.9; Acetoacetyl-CoA thiolase
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    31-424
  • 氨基酸序列
    ASKPTLNEVV IVSAIRTPIG SFLGSLASQP ATKLGTAAIQ GAIEKAGIPK EEVKEVYMGN VIQGGEGQAP TRQATLGAGL PISTPCTTVN KVCASGMKAI MMASQSLMCG HQDVMVAGGM ESMSNVPYVM SRGATPYGGV KLEDLIVKDG LTDVYNKIHM GNCAENTAKK MNISRQEQDT YALSSYTRSK EAWDAGKFAS EITPITISVK GKPDVVVKED EEYKRVDFSK VPKLKTVFQK ENGTITAANA STLNDGAAAL VLMTAEAAQR LNVKPLARIA AFADAAVDPI DFPLAPAYAV PKVLKYAGLK KEDIAMWEVN EAFSVVVLAN IKMLEIDPQK VNIHGGAVSL GHPIGMSGAR IVVHMAHALK PGEFGLASIC NGGGGASALL IEKL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism.
  • 基因功能參考文獻：
    1. Data show that microRNA miR-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 3' untranslated regions (3'UTR). PMID: 27678191
    2. In a mouse model, targeting ACAT1 specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages. PMID: 26801614
    3. Its blockage enhances autophagy of and reduces human p301L-tau content in brain neurons of pre-symptomatic stage of Alzheimer disease. PMID: 25930235
    4. Oxidized low-density lipoprotein activated the TLR4/MyD88/NF-kappaB inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 expression and promotes VSMC foam cell formation. PMID: 25522268
    5. Exacerbation of liver fibrosis by ACAT1 deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 signaling. PMID: 24657401
    6. ACAT1 plays important roles in hematopoiesis in normal mouse and in Apoe(-/-) mouse during atherosclerosis development. PMID: 23846496
    7. ApoA-I Helsinki promotes accumulation of ACAT1 in a mouse macrophage cell line. PMID: 23456478
    8. the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT inhibition in addition to potent inhibition of macrophage ACAT-1 PMID: 20843517
    9. ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease. PMID: 20133765
    10. ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol PMID: 12975367
    11. ACAT1 knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1. PMID: 15845358
    12. Deficiency of macrophage ACAT1 accelerates atherosclerosis in apoE-/- mice but has no effect when hypercholesterolemia is corrected by apoE expression. ACAT1 deletion impairs ABCA1-mediated cholesterol efflux in macrophages regardless of apoE expression PMID: 15851589
    13. sitosterol-induced macrophage death does not require ACAT dysfunction and so may occur in an accelerated fashion PMID: 16935859
    14. Report differential effects of PARP-1 inhibition on vascular cell survival and ACAT-1 expression favouring atherosclerotic plaque stability. PMID: 18245064

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Thiolase family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产亚洲产品影市在线产品| 久久国产精品一国产精品 | 人人妻人人爽人人做夜欢视频九色| 欧美日本特级婬片视频| 国产男女猛烈无遮挡免费视频网站 | 欧美巨大xxxx做受中文字幕| 久久中文骚妇内射| 精品亚洲麻豆1区2区3区| 亚洲精品国产精品乱码视色| 国产丝袜足j在线视频播放| 久久人妻国产精品| 日韩免费无砖专区2020狼| 亚洲精品久久久久中文字幕二区| 69精品丰满人妻无码视频a片| 国产日韩精品欧美一区喷水| 无码少妇高潮浪潮av久久| 久久精品人人做人人综合| 免费人成在线观看视频高潮| 国产成人精品日本亚洲77上位| 久久亚洲中文字幕精品一区| 东北老女人高潮大喊舒服死了| 日韩精品久久久免费观看| 亚洲人成中文字幕在线观看 | 黄网站免费永久在线观看下载| 热re99久久精品国产99热| 在线播放国产一区二区三区| 亚洲国产成人精品青青草原| 两性色午夜视频免费老司机| 欧美精品videosbestsex日本| 成年美女黄网站色大片免费看| 99久久婷婷国产综合精品 | 国产精品 无码专区| 日韩一区二区三区射精| 正在播放国产真实露脸高清| 欧美老妇大p毛茸茸| 欧洲美熟女乱又伦免费视频| 亚洲欧美综合精品二区| 天天躁日日躁狠狠躁av中文| 无码国产乱人伦偷精品视频| 亚洲美女视频高清在线看| 免费国产裸体美女视频全黄|