在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse A-kinase anchor protein 12 (Akap12), partial

Recombinant Mouse A-kinase anchor protein 12 (Akap12), partial

  • 中文名稱：
    Recombinant Mouse A-kinase anchor protein 12(Akap12) ,partial
  • 貨號(hào)：
    CSB-YP896230MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse A-kinase anchor protein 12(Akap12) ,partial
  • 貨號(hào)：
    CSB-EP896230MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse A-kinase anchor protein 12(Akap12) ,partial
  • 貨號(hào)：
    CSB-EP896230MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse A-kinase anchor protein 12(Akap12) ,partial
  • 貨號(hào)：
    CSB-BP896230MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse A-kinase anchor protein 12(Akap12) ,partial
  • 貨號(hào)：
    CSB-MP896230MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Akap12
  • Uniprot No.：
  • 別名：
    Akap12; Gag12; Ssecks; A-kinase anchor protein 12; AKAP-12; Germ cell lineage protein gercelin; Src-suppressed C kinase substrate; SSeCKS
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
  • 基因功能參考文獻(xiàn)：
    1. fibrosis induced by Ang II may be alleviated by AKAP12 expression through inactivation of the TGF-beta1 pathway. PMID: 29501491
    2. gravin is an important component of cardiac contraction PMID: 28428008
    3. The enrichment of activated Cdc42 in SSeCKS-null leading edge filopodia correlated with recruitment of the Cdc42-specific guanine nucleotide exchange factor, Frabin. PMID: 25356636
    4. AKAP12 scaffolding protein mediates meningeal reconstruction after central nervous system injury PMID: 25229625
    5. Results suggest that AKAP12-positive cells in the fibrotic scar may restrict excessive inflammation, demonstrating mechanisms that could underlie the beneficial actions of the fibrotic scar in the new tissue formation stage during the CNS repair process. PMID: 24760034
    6. Disruption of gravin's scaffold mediated signaling is able to increase baseline cardiac function as well as to augment contractility in response to acute beta-AR stimulation. PMID: 24058627
    7. We conclude that gravin compartmentalizes a significant pool of PKA that regulates learning-induced beta2-adrenergic receptor signaling and ERK activation in the hippocampus PMID: 23238728
    8. Our study implicates a role for SSeCKS in preventing of skin cancer progression possibly through negatively regulating FAK expression. PMID: 21128249
    9. controls the localization and activity of cyclin D1 in parietal epithelial cells and influences proliferative injury in the glomerulus PMID: 22249313
    10. PKC-mediated remodeling of the actin cytoskeleton is likely regulated by the ability of SSeCKS to control PKC signaling and activity through a direct scaffolding function PMID: 21903576
    11. Akap12 controls Rb-mediated cell aging and oncogenic progression by directly scaffolding and attenuating PKCalpha/delta. PMID: 21099353
    12. SERPINB5 and AKAP12 may have a role in increased metastasis in pancreatic ductal adenocarcinoma PMID: 20939879
    13. induced in vascular endothelial cells by bacterial lipopolysaccharide PMID: 11799143
    14. SSeCKS has a restricted distribution within the nervous system and that expression of this protein may reflect the specific signaling requirements of a distinct population of nociceptive sensory neurons. PMID: 11814414
    15. Phosphorylation of SSeCKS by mitogenically activated kinases decreases intrinsic cell scaffolding activities and suggests that SSeCKS regulatory functions are lost in the late G1 phase. PMID: 11820772
    16. a role for SSeCKS in mitogen-induced cytoskeletal reorganization. PMID: 12083796
    17. SSeCKS expression in endothelial cells and reticular cells is a functional index of the reticulo-endothelial system PMID: 15468953
    18. alternately targeted anchoring protein isoforms provide a mechanism for genetic control of signaling specificity by AKAP12 PMID: 15496411
    19. AKAP12alpha belongs to a novel class of atypical SRF-dependent target genes PMID: 15590635
    20. v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex. PMID: 17626016
    21. SSeCKS-null mice have increased susceptibility for oncogenic transformation in the prostate. PMID: 18593908

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Membrane; Lipid-anchor.
  • 組織特異性：
    Isoform 1 is predominantly found in the nervous system. Isoform 3 is testis specific.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 亚洲337少妇裸体艺术| 免费看成人啪啪| 天天噜日日噜狠狠噜免费| 黑人狠狠的挺身进入| 日本工口里番无遮█彩色| 亚洲欧美国产国产一区二区三区 | 欧美亚洲高清国产| 风间由美性色一区二区三区| 久久精品人妻一区二区蜜桃| 18禁黄网站禁片免费观看国产 | 国产揄拍国产精品| 亚洲成aⅴ人最新无码 | 无码 制服 丝袜 国产 另类| 亚洲成a人片在线观看高清| 色婷婷我要去我去也| 国产精品高潮呻吟av久久男男| 国产偷窥熟妇高潮呻吟| 亚洲妇女无套内射精| 无码少妇一区二区三区浪潮av| 波多野av一区二区无码| 人妻 色综合网站| 亚洲日韩成人性av网站| 99久久免费国产精品| 亚洲精品偷拍影视在线观看 | 国产免码va在线观看免费 | 蜜桃精品成人影片| 2020最新国产在线不卡a| 97夜夜澡人人双人人人喊| 玩弄人妻少妇500系列| 人妻少妇av无码一区二区| 国产线观看免费观看| 99久久超碰中文字幕伊人| 男女啪动最猛动态图| 人禽杂交18禁网站免费| 青草精品国产福利在线视频 | 777亚洲精品乱码久久久久久| 全黄h全肉边做边吃奶视频| 亚洲最新版av无码中文字幕| 精品人妻伦一二三区久久aaa片| 东京热加勒比无码少妇| 偷看少妇自慰xxxx|