在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4 (Adamts4)

Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4 (Adamts4)

  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4(Adamts4)
  • 貨號：
    CSB-YP805312MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4(Adamts4)
  • 貨號：
    CSB-EP805312MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4(Adamts4)
  • 貨號：
    CSB-EP805312MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4(Adamts4)
  • 貨號：
    CSB-BP805312MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 4(Adamts4)
  • 貨號：
    CSB-MP805312MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Adamts4A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM-TS 4; ADAM-TS4; ADAMTS-4; EC 3.4.24.82; Aggrecanase-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    209-833
  • 氨基酸序列
    FA SLSRFVETLV VADDKMAAFH GTGLKRYLLT VMAAAAKAFK HPSIRNPVNL VVTRLVILGS GQEGPQVGPS AAQTLRSFCT WQRGLNTPND SDPDHFDTAI LFTRQDLCGV STCDTLGMAD VGTVCDPARS CAIVEDDGLQ SAFTAAHELG HVFNMLHDNS KPCTNLNGQG GSSRHVMAPV MAHVDPEEPW SPCSARFITD FLDNGYGHCL LDKPEAPLHL PATFPGKDYD ADRQCQLTFG PDSSHCPQLP PPCAALWCSG HLNGHAMCQT KHSPWADGTP CGSSQACMGG RCLHVDQLKD FNVPQAGGWG PWGPWGDCSR TCGGGVQFSS RDCTRPVPRN GGKYCEGRRT RFRSCNTENC PHGSALTFRE EQCAAYNHRT DLFKSFPGPM DWVPRYTGVA PRDQCKLTCQ ARALGYYYVL EPRVADGTPC SPDTSSVCVQ GRCIHAGCDR IIGSKKKFDK CMVCGGDGSR CSKQSGSFKK FRYGYSDVVT IPAGATHILV RQQGGSGLKS IYLALKLSDG SYALNGEYTL MPSPTDVVLP GAVSLRYSGA TAASETLSGH GPLAQPLTLQ VLVAGNPQNA RLRYSFFVPR PVPSTPRPPP QDWLQRRAEI LKILRKRPWA GRK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
  • 基因功能參考文獻：
    1. host-derived ADAMTS4 was expressed at the tumor vessels and was associated with early-stage tumor growth. PMID: 29926003
    2. This study demonstrated that ADAMTS-4 is a new marker of mature oligodendrocytes contributing to the myelination processes and thus to the control of motor capacities. PMID: 28850711
    3. results demonstrate for the first time that ADAMTS4 contributes to diet induced atherosclerosis in ApoE(-/-) mice PMID: 27491335
    4. the reduction of ADAMTS-4 activity during the progression of ALS pathology may be an adaptive change to mitigate its neurodegenerative impact in CNS tissues PMID: 26809777
    5. aggrecan and brevican proteolysis is compensated in Adamts4-/- or Adamts5-/- mice by ADAMTS proteoglycanase family members but a threshold of versican proteolysis is sensitive to the loss of a single ADAMTS proteoglycanase during spinal cord injury PMID: 25101296
    6. ADAMTS4 has roles in melanoma growth and angiogenesis in mice PMID: 23319426
    7. The serine protease tissue plasminogen activator (tPA) and two matrix metalloproteinases, ADAMTS-4 and ADAMTS-5, were identified as Reelin cleaving enzymes. PMID: 23082219
    8. ADAMTS-4 cleaves Reelin in an isoform-specific manner. Among ADAMTS-4 isoforms, p50 cleaves the N-t site only, while p75 cleaves both sites. PMID: 22819337
    9. Data demonstrate that Adamts1 and Adamts4 play redundant and essential roles in perinatal kidney development. PMID: 21584905
    10. Drastic down-regulation of Adamts4 observed at both E16 and E18; RT-PCR revealed post-natal reduction in expression (Adamts4, 1/3). Results suggest down-regulation of gene is important factor in normal odontogenesis in dental papillae. PMID: 20448247
    11. proteolysis of hevin by ADAMTS4 in the mouse cerebellum is important for the normal development of this tissue PMID: 20018883
    12. ADAMTS1, ADAMTS4, and ADAMTS5 are expressed in patterns that relate to the expression pattern of versican in granulosa cells of small follicles, expanded cumulus cell-oocyte complexes, and endothelial cells of the ovary. PMID: 15659705
    13. ADAMTS-5 is entirely responsible for cleavage in the interglobular domain, but cleavage in the chondroitin sulfate-rich region may be driven by ADAMTS-4 PMID: 17255106
    14. comparison of aggrecan loss with aggrecan processing in mice with single and double deletions of ADAMTS-4 and -5 activity (Deltacat) PMID: 17938173
    15. Deletion of ADAMTS-4/5 provided significant protection against proteoglycan degradation ex vivo and decreased the severity of murine osteoarthritis PMID: 17968948

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 數據庫鏈接：


主站蜘蛛池模板： 特黄特色的大片观看免费视频| 亚洲精品久久久久玩吗| 丰满五十六十老熟女hd| 色欲精品国产一区二区三区av| 欧美激情猛片xxxⅹ大3| 国内自拍久久久久影院| 亚洲美女又黄又爽在线观看| 国产无套乱子伦精彩是白视频| 亚洲乱码无人区卡1卡2卡3| 男女啪啦猛视频免费| 豆国产95在线 | 亚洲| 亚洲最大无码中文字幕| 精品婷婷色一区二区三区| 亚洲综合久久无码色噜噜| 天天躁夜夜躁av天天爽| 日本簧片在线观看| 97国语精品自产拍在线观看| 欧美xxxx欧美精品| 国产人妻一区二区三区久| 成人国产mv免费视频| 免费国产午夜视频在线观看| 午夜精品乱人伦小说区| 色护士极品影院| 无码精品国产一区二区免费| 正在播放国产剧情亂倫| 国产精品沙发午睡系列| 中文在线а天堂| 韩国三级l中文字幕无码| 国产精品日韩欧美一区二区三区| 免费人妻精品一区二区三区 | 中文字幕丝袜精品久久| 中国猛少妇色xxxxx| 唐人社导航福利精品| 亚洲综合色区无码专区| 国产成人亚洲精品无码青青草原| 午夜天堂av天堂久久久| 久久亚洲一区二区三区四区五区 | 丁香五月亚洲综合在线| 日本中文字幕一区二区有码在线| 欧美成人精品一区二区三区色欲| 麻豆av一区二区天美传媒|