Recombinant Mesobuthus tamulus Potassium channel toxin alpha-KTx 5.4

中文名稱：

Recombinant Mesobuthus tamulus Potassium channel toxin alpha-KTx 5.4
貨號：

CSB-YP352984MRF
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mesobuthus tamulus Potassium channel toxin alpha-KTx 5.4
貨號：

CSB-EP352984MRF
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mesobuthus tamulus Potassium channel toxin alpha-KTx 5.4
貨號：

CSB-EP352984MRF-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mesobuthus tamulus Potassium channel toxin alpha-KTx 5.4
貨號：

CSB-BP352984MRF
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mesobuthus tamulus Potassium channel toxin alpha-KTx 5.4
貨號：

CSB-MP352984MRF
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

N/A
Uniprot No.：

P59869
別名：

Potassium channel toxin alpha-KTx 5.4; Tamapin
種屬：

Mesobuthus tamulus (Eastern Indian scorpion) (Buthus tamulus)
蛋白長度：

Cytoplasmic domain
表達區(qū)域：

1-31
氨基酸序列

AFCNLRRCEL SCRSLGLLGK CIGEECKCVP Y
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Blocks small conductance calcium-activated potassium channels. Shows activity on KCa2.2/KCNN2 (IC(50)=0.0243 nM), KCa2.3/KCNN3 (IC(50)=1.7 nM), and KCa2.1/KCNN1 (IC(50)=42 nM). Induces cell death when tested on Jurkat E6-1 and human mammary breast cancer MDA-MB-231 which constituvely express KCa2.2/KCNN2, but not on human peripheral blood lymphocytes (which do not express KCa2.2/KCNN2).
亞細(xì)胞定位：

Secreted.
蛋白家族：

Short scorpion toxin superfamily, Potassium channel inhibitor family, Alpha-KTx 05 subfamily
組織特異性：

Expressed by the venom gland.