在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Macaca fascicularis Heat shock protein HSP 90-beta (Hsp90ab1), partial

  • 中文名稱:
    獼猴Hsp90ab1重組蛋白
  • 貨號:
    CSB-YP686992MOV1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    獼猴Hsp90ab1重組蛋白
  • 貨號:
    CSB-EP686992MOV1
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    獼猴Hsp90ab1重組蛋白
  • 貨號:
    CSB-EP686992MOV1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    獼猴Hsp90ab1重組蛋白
  • 貨號:
    CSB-BP686992MOV1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    獼猴Hsp90ab1重組蛋白
  • 貨號:
    CSB-MP686992MOV1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HSP90AB1; QccE-21185; Heat shock protein HSP 90-beta
  • 種屬:
    Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone. After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from HSP90 which acquires an open conformation for the next cycle. Apart from its chaperone activity, it also plays a role in the regulation of the transcription machinery. HSP90 and its co-chaperones modulate transcription at least at three different levels. They first alter the steady-state levels of certain transcription factors in response to various physiological cues. Second, they modulate the activity of certain epigenetic modifiers, such as histone deacetylases or DNA methyl transferases, and thereby respond to the change in the environment. Third, they participate in the eviction of histones from the promoter region of certain genes and thereby turn on gene expression. Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation. Promotes cell differentiation by chaperoning BIRC2 and thereby protecting from auto-ubiquitination and degradation by the proteasomal machinery. Main chaperone involved in the phosphorylation/activation of the STAT1 by chaperoning both JAK2 and PRKCE under heat shock and in turn, activates its own transcription. Involved in the translocation into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) of leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1; the translocation process is mediated by the cargo receptor TMED10.
  • 亞細胞定位:
    Cytoplasm. Melanosome. Nucleus. Secreted. Cell membrane. Dynein axonemal particle.
  • 蛋白家族:
    Heat shock protein 90 family
  • 數(shù)據(jù)庫鏈接:

    KEGG: mcf:101926380

    UniGene: Mfa.8483



主站蜘蛛池模板: 中出人妻中文字幕无码| 一本无码人妻在中文字幕| 理论片午午伦夜理片影院99| 好男人社区资源| 亚洲国产专区校园欧美| 中文字幕免费无码专区| av鲁丝一区鲁丝二区鲁丝三区| 日本精品少妇一区二区三区 | 日本熟妇色xxxxxhd| 国色天香精品一卡2卡3卡4| 久久综合九色综合国产| 最新精品香蕉在线| 欧美又大又粗午夜剧场免费| 韩国三级hd中文字幕叫床 | 99久久精品美女高潮喷水| 国产人妻精品区一区二区三区| 亚洲精品久久久久一区二区三区 | 婷婷丁香五月亚洲中文字幕| 欧美深度肠交惨叫| 丰满多毛的大隂户毛茸茸| 欧美精品videossex另类日本| 国产黑色丝袜在线看片不卡顿| 亚洲精品无码不卡| 国产蝌蚪视频一区二区三区 | 无套内谢的新婚少妇国语播放 | 国产日韩欧美亚欧在线观看| 国产精品v片在线观看不卡 | 国产精品久久久国产盗摄| 国产欧美另类久久久精品丝瓜| 特级做a爰片毛片免费看| 久久久久无码精品国产不卡| 亚洲精品无码av中文字幕电影网站| 真人啪啪高潮喷水呻吟无遮挡| 日韩人妻一区二区三区蜜桃视频| 国产真实露脸乱子伦原著| 人人玩人人添人人澡欧美| 精品无码av一区二区三区不卡| 99这里只有精品| 国产欧美va天堂在线电影| 国产裸体xxxx视频| 日产电影一区二区三区|