在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Macaca fascicularis Dual specificity tyrosine-phosphorylation-regulated kinase 3 (DYRK3), partial

  • 中文名稱:
    獼猴DYRK3重組蛋白
  • 貨號:
    CSB-YP687019MOV
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    獼猴DYRK3重組蛋白
  • 貨號:
    CSB-EP687019MOV
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    獼猴DYRK3重組蛋白
  • 貨號:
    CSB-EP687019MOV-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    獼猴DYRK3重組蛋白
  • 貨號:
    CSB-BP687019MOV
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    獼猴DYRK3重組蛋白
  • 貨號:
    CSB-MP687019MOV
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DYRK3
  • Uniprot No.:
  • 別名:
    DYRK3; QtsA-17232Dual specificity tyrosine-phosphorylation-regulated kinase 3; EC 2.7.12.1
  • 種屬:
    Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Dual-specificity protein kinase that promotes disassembly of several types of membraneless organelles during mitosis, such as stress granules, nuclear speckles and pericentriolar material. Dual-specificity tyrosine-regulated kinases (DYRKs) autophosphorylate a critical tyrosine residue in their activation loop and phosphorylate their substrate on serine and threonine residues. Acts as a central dissolvase of membraneless organelles during the G2-to-M transition, after the nuclear-envelope breakdown: acts by mediating phosphorylation of multiple serine and threonine residues in unstructured domains of proteins, such as SRRM1 and PCM1. Does not mediate disassembly of all membraneless organelles: disassembly of P-body and nucleolus is not regulated by DYRK3. Dissolution of membraneless organelles at the onset of mitosis is also required to release mitotic regulators, such as ZNF207, from liquid-unmixed organelles where they are sequestered and keep them dissolved during mitosis. Regulates mTORC1 by mediating the dissolution of stress granules: during stressful conditions, DYRK3 partitions from the cytosol to the stress granule, together with mTORC1 components, which prevents mTORC1 signaling. When stress signals are gone, the kinase activity of DYRK3 is required for the dissolution of stress granule and mTORC1 relocation to the cytosol: acts by mediating the phosphorylation of the mTORC1 inhibitor AKT1S1, allowing full reactivation of mTORC1 signaling. Also acts as a negative regulator of EPO-dependent erythropoiesis: may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1: this in turn inhibits p53/TP53 activity and apoptosis.
  • 亞細胞定位:
    Nucleus. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
  • 蛋白家族:
    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily
  • 數據庫鏈接:

    KEGG: mcf:101866219

    UniGene: Mfa.1253



主站蜘蛛池模板: 呦男呦女视频精品八区| 亚洲老妇色熟女老太| 国产 一二三四五六| 国产嘿嘿嘿视频在线观看| 国产成人亚洲精品无码青青草原| 国产精品久久欧美久久一区| 日本最新免费二区三区| 97成人精品国语自产拍| 噜噜色综合天天综合网mp3| 超薄丝袜足j好爽在线| 熟妇女人妻丰满少妇中文字幕| 欧美xxxx狂喷水| 亚洲国产精品无码一区二区三区| 在教室伦流澡到高潮hgl视频| 麻豆一区二区三区精品视频| 中文字幕婷婷日韩欧美亚洲| 高中生粉嫩无套第一次| 久久精品国产69国产精品亚洲| 国产内射合集颜射| 婷婷五月深爱综合开心网| 亚洲精品无码鲁网午夜| 亚洲乱码国产乱码精品精| 亚洲午夜免费福利视频| 亚洲精品无码乱码成人| 亚洲色欲色欲大片www无码| 精品国产av色一区二区深夜久久| 久久不见久久见www免费| 午夜福利视频1692| 成年美女黄网站色大免费视频| 又大又粗又爽18禁免费看| 色情无码www视频无码区澳门| 亚洲伊人成综合网| 日韩一区二区三区无码影院| 免费永久看黄神器无码软件| 很黄很黄的曰批视频| 国内精品自在自线| 国产女人高潮嗷嗷嗷叫| 久久成人伊人欧洲精品| 五月丁香六月综合av| 3p人妻少妇对白精彩视频| 国产亚洲曝欧美曝妖精品|