在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human tRNA methyltransferase 10 homolog C (TRMT10C)

  • 中文名稱:
    人TRMT10C重組蛋白
  • 貨號:
    CSB-YP748718HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TRMT10C重組蛋白
  • 貨號:
    CSB-EP748718HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TRMT10C重組蛋白
  • 貨號:
    CSB-EP748718HU-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TRMT10C
  • Uniprot No.:
  • 別名:
    TRMT10C; MRPP1; RG9MTD1tRNA methyltransferase 10 homolog C; HBV pre-S2 trans-regulated protein 2; Mitochondrial ribonuclease P protein 1; Mitochondrial RNase P protein 1; RNA; guanine-9-)-methyltransferase domain-containing protein 1; Renal carcinoma antigen NY-REN-49; mRNA methyladenosine-N(1)-methyltransferase; EC 2.1.1.-; tRNA; adenine(9)-N(1))-methyltransferase; EC 2.1.1.218; tRNA; guanine(9)-N(1))-methyltransferase; EC 2.1.1.221
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    40-403
  • 氨基酸序列
    M SSKIPAVTYP KNESTPPSEE LELDKWKTTM KSSVQEECVS TISSSKDEDP LAATREFIEM WRLLGREVPE HITEEELKTL MECVSNTAKK KYLKYLYTKE KVKKARQIKK EMKAAAREEA KNIKLLETTE EDKQKNFLFL RLWDRNMDIA MGWKGAQAMQ FGQPLVFDMA YENYMKRKEL QNTVSQLLES EGWNRRNVDP FHIYFCNLKI DGALHRELVK RYQEKWDKLL LTSTEKSHVD LFPKDSIIYL TADSPNVMTT FRHDKVYVIG SFVDKSMQPG TSLAKAKRLN LATECLPLDK YLQWEIGNKN LTLDQMIRIL LCLKNNGNWQ EALQFVPKRK HTGFLEISQH SQEFINRLKK AKT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mitochondrial tRNA N(1)-methyltransferase involved in mitochondrial tRNA maturation. Component of mitochondrial ribonuclease P, a complex composed of TRMT10C/MRPP1, HSD17B10/MRPP2 and PRORP/MRPP3, which cleaves tRNA molecules in their 5'-ends. Together with HSD17B10/MRPP2, forms a subcomplex of the mitochondrial ribonuclease P, named MRPP1-MRPP2 subcomplex, which displays functions that are independent of the ribonuclease P activity. The MRPP1-MRPP2 subcomplex catalyzes the formation of N(1)-methylguanine and N(1)-methyladenine at position 9 (m1G9 and m1A9, respectively) in tRNAs; TRMT10C/MRPP1 acting as the catalytic N(1)-methyltransferase subunit. The MRPP1-MRPP2 subcomplex also acts as a tRNA maturation platform: following 5'-end cleavage by the mitochondrial ribonuclease P complex, the MRPP1-MRPP2 subcomplex enhances the efficiency of 3'-processing catalyzed by ELAC2, retains the tRNA product after ELAC2 processing and presents the nascent tRNA to the mitochondrial CCA tRNA nucleotidyltransferase TRNT1 enzyme. In addition to tRNA N(1)-methyltransferase activity, TRMT10C/MRPP1 also acts as a mRNA N(1)-methyltransferase by mediating methylation of adenosine residues at the N(1) position of MT-ND5 mRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.
  • 基因功能參考文獻:
    1. in addition to being an essential component of the RNase P reaction, MRPP1/2 serves as a processing platform for several down-stream tRNA maturation steps in human mitochondria. PMID: 29040705
    2. identifying mutations in TRMT10C as a cause of mitochondrial disease and highlighting the importance of RNA processing for correct mitochondrial function PMID: 27132592
    3. Inhibition of mitochondrial RNase P by beta-amyloid is an unspecific effect and is not mediated by beta-amyloid interaction with SDR5C1. PMID: 23755257
    4. MRPP1 is essential for transcript processing, RNA modification, translation and mitochondrial respiration. PMID: 21857155
    5. We also identify the 5' and 3' transcript ends of the three lncRNAs and show that mitochondrial RNase P protein 1 (MRPP1) is important for the processing of these transcripts. PMID: 22028365

    顯示更多

    收起更多

  • 相關疾病:
    Combined oxidative phosphorylation deficiency 30 (COXPD30)
  • 亞細胞定位:
    Mitochondrion matrix, mitochondrion nucleoid.
  • 蛋白家族:
    Class IV-like SAM-binding methyltransferase superfamily, TRM10 family
  • 數據庫鏈接:

    HGNC: 26022

    OMIM: 615423

    KEGG: hsa:54931

    STRING: 9606.ENSP00000312356

    UniGene: Hs.594839



主站蜘蛛池模板: 精品一卡2卡三卡4卡乱码精品视频| www成人国产高清内射| 亚洲国产欧美在线人成| 成年男女免费视频网站| 蜜桃视频网站| 伊人久久成综合久久影院| 精品一区二区三区国产在线观看| 日韩在线 | 中文| 无码国产精品一区二区免费16| 影音先锋女人av鲁色资源网久久| 免费人成年激情视频在线观看| 国产美女视频免费观看的网站| 尹人香蕉99久久综合网站| 国产熟女高潮视频| 国产精品久久久久久妇女6080| 国产猛男猛女超爽免费视频| 秋霞av在线露丝片av无码| 国内精品自线在拍2020不卡| 久久aⅴ人妻少妇嫩草影院| 小说区 图片区色 综合区 | 中国女人内射6xxxxx| 国产精品成人嫩草影院| 少妇久久久久久人妻无码| 一二三四区无产乱码1000集| 99精品无人区乱码在线观看| 久久久综合香蕉尹人综合网 | 午夜成人影院网站18进| 伊人久久大香线蕉影院| 国产又粗又硬又大爽黄老大爷视频| 日本最新免费二区| 免费看撕开奶罩揉吮奶头视频| 国产免码va在线观看免费| 国模精品一区二区三区| 永久免费的av片在线电影网| 涩里番网污站| 欧美性猛交久久久乱大交小说| 全球av集中精品导航福利| 色老99久久九九爱精品| 裸体丰满白嫩大尺度尤物| ā片在线观看免费观看| 国产95在线 | 欧美|