在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human immunodeficiency virus type 1 group M subtype B Envelope glycoprotein gp160 (env), partial

  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Envelope glycoprotein gp160(env) ,partial
  • 貨號(hào):
    CSB-YP322698HKS
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Envelope glycoprotein gp160(env) ,partial
  • 貨號(hào):
    CSB-EP322698HKS
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Envelope glycoprotein gp160(env) ,partial
  • 貨號(hào):
    CSB-EP322698HKS-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Envelope glycoprotein gp160(env) ,partial
  • 貨號(hào):
    CSB-BP322698HKS
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Envelope glycoprotein gp160(env) ,partial
  • 貨號(hào):
    CSB-MP322698HKS
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    env
  • Uniprot No.:
  • 別名:
    envEnvelope glycoprotein gp160; Env polyprotein) [Cleaved into: Surface protein gp120; SU; Glycoprotein 120; gp120); Transmembrane protein gp41; TM; Glycoprotein 41; gp41)]
  • 種屬:
    Human immunodeficiency virus type 1 group M subtype B (isolate JRCSF) (HIV-1)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.; Attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. Acts as a ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses. These interactions allow capture of viral particles at mucosal surfaces by these cells and subsequent transmission to permissive cells. HIV subverts the migration properties of dendritic cells to gain access to CD4+ T-cells in lymph nodes. Virus transmission to permissive T-cells occurs either in trans (without DCs infection, through viral capture and transmission), or in cis (following DCs productive infection, through the usual CD4-gp120 interaction), thereby inducing a robust infection. In trans infection, bound virions remain infectious over days and it is proposed that they are not degraded, but protected in non-lysosomal acidic organelles within the DCs close to the cell membrane thus contributing to the viral infectious potential during DCs' migration from the periphery to the lymphoid tissues. On arrival at lymphoid tissues, intact virions recycle back to DCs' cell surface allowing virus transmission to CD4+ T-cells.; Acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane. The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
  • 亞細(xì)胞定位:
    [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein.; [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    HIV-1 env protein family


主站蜘蛛池模板: 一本大道久久香蕉成人网| 熟妇人妻av无码一区二区三区 | 人禽无码视频在线观看| 欧美成人一区二区三区在线视频| 久久久亚洲欧洲日产av| 手机看片精品国产福利| 最近的中文字幕在线看视频| 国产福利一区二区三区在线观看| 日本少妇肉体裸交xxx| 伊人无码精品久久一区二区| 亚洲 小说 欧美 另类 社区| 国产成人av一区二区在线观看| 天码av无码一区二区三区四区| 日产精品高潮呻吟av久久| 国产成人人综合亚洲欧美丁香花| 免费裸体无遮挡黄网站免费看| а√天堂www在线天堂小说| 成人亚洲a片v一区二区三区蜜臀| 免费啪视频在线观看视频日本| 337p日本欧洲亚洲大胆69影院| 亚洲爆乳无码精品aaa片蜜桃| 久久久综合香蕉尹人综合网| 精品国产一二三产品区别在哪| 人人莫人人擦人人看| 五月婷婷久久草丁香| 亚洲色成人www永久网站| 亚洲一区波多野结衣在线| 日本 精品 高清不卡| 国产精品午夜无码av天美传媒| 久久人人爽人人爽人人片| av狠狠色超碰丁香婷婷综合久久| 国产亚洲日韩妖曝欧美| 欧美多毛肥胖老妇做爰| 少妇愉情理伦片高潮日本| 国产成人av激情在线播放| 涩涩鲁亚洲精品一区二区| 宅宅少妇无码| 欧美黑人巨大videos在线| 无码三级中文字幕在线观看| 理论片午午伦夜理片影院99| 99久久精品无码一区二区毛片|