在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein

  • 中文名稱:
    Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein
  • 貨號:
    CSB-YP861650HFAY
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein
  • 貨號:
    CSB-EP861650HFAY
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein
  • 貨號:
    CSB-EP861650HFAY-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein
  • 貨號:
    CSB-BP861650HFAY
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein
  • 貨號:
    CSB-MP861650HFAY
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Genome polyprotein [Cleaved into: Protein VP0; VP4-VP2); Protein VP4; P1A; Virion protein 4); Capsid protein VP2; P1B; Virion protein 2); Capsid protein VP3; P1C; Virion protein 3); Protein VP1-2A; VPX); Capsid protein VP1; P1D; Virion protein 1); Assembly signal 2A; pX); Protein 2BC; Protein 2B; P2B); Protein 2C; P2C; EC 3.6.1.15); Protein 3ABCD; P3); Protein 3ABC; Protein 3AB; Protein 3A; P3A); Viral protein genome-linked; VPg; Protein 3B; P3B); Protein 3CD; Protease 3C; P3C; EC 3.4.22.28; Picornain 3C); RNA-directed RNA polymerase 3D-POL; P3D-POL; EC 2.7.7.48)]
  • 種屬:
    Human hepatitis A virus genotype IIIA (isolate NOR-21) (HHAV) (Human hepatitis A virus (isolate Human/Norway/NOR-21/1998))
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-245
  • 氨基酸序列
    MNMSRQGIFQ TVGSGLDHIL SLADVEEEQM IQSVDRTAVT GASYFTSVDQ SSVHTAEVGS HQPEPLKTSV DKPGSKRTQG EKFFLIHSAD WLTTHALFHE VAKLDVVKLL YNEQFAVQGL LRYHTYARFG IEIQVQINPT PFQQGGLICA MVPGDQSYGS IASLTVYPHG LLNCNINNVV RIKVPFIYTR GAYHFKDPQY PVWELTIRVW SELNIGTGTS AYTSLNVLAR FTDLELHGLT PLSTQ
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell.; Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell.; Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell.; VP0 precursor is a component of the immature procapsids.; Plays a role in the assembly of the 12 pentamers into an icosahedral structure. Has not been detected in mature virions, supposedly owing to its small size.; Precursor component of immature procapsids that corresponds to an extended form of the structural protein VP1. After maturation, possibly by the host Cathepsin L, the assembly signal 2A is cleaved to give rise to the mature VP1 protein.; Functions as a viroporin. Affects membrane integrity and causes an increase in membrane permeability. Involved in host intracellular membrane rearrangements probably to give rise to the viral factories. Does not disrupt calcium homeostasis or glycoprotein trafficking. Antagonizes the innate immune response of the host by suppressing IFN-beta synthesis, which it achieves by interfering with the DDX58/IFIH1 (RIG-I/MDA5) pathway.; Affects membrane integrity and causes an increase in membrane permeability.; Associates with and induces structural rearrangements of intracellular membranes. Displays RNA-binding activity.; The precursor 3ABC is targeted to the mitochondrial membrane where protease 3C activity cleaves and inhibits the host antiviral protein MAVS, thereby disrupting activation of IRF3 through the IFIH1/MDA5 pathway. In vivo, the protease activity of 3ABC precursor is more efficient in cleaving the 2BC precursor than that of protein 3C. The 3ABC precursor may therefore play a role in the proteolytic processing of the polyprotein. Possible viroporin.; Interacts with the 3CD precursor and with RNA structures found at both the 5'- and 3'-termini of the viral genome. Since the 3AB precursor contains the hydrophobic domain 3A, it probably anchors the whole viral replicase complex to intracellular membranes on which viral RNA synthesis occurs.; May serve as membrane anchor to the 3AB and 3ABC precursors via its hydrophobic domain. May interact with RNA.; Acts as a primer for viral RNA replication and remains covalently bound to viral genomic RNA. VPg is uridylylated prior to priming replication into VPg-pUpU. The VPg-pUpU is then used as primer on the genomic RNA poly(A) by the RNA-dependent RNA polymerase to replicate the viral genome.; Cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind cooperatively to the protease. Cleaves IKBKG/NEMO to impair innate immune signaling. Cleaves host PABPC1 which may participate in the switch of viral translation to RNA synthesis.; Interacts with the 3AB precursor and with RNA structures found at both the 5'- and 3'-termini of the viral genome. Disrupts TLR3 signaling by degrading the host adapter protein TICAM1/TRIF.; RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals.
  • 亞細(xì)胞定位:
    [Capsid protein VP2]: Virion. Host endosome, host multivesicular body.; [Capsid protein VP3]: Virion. Host endosome, host multivesicular body.; [Capsid protein VP1]: Virion. Host endosome, host multivesicular body.; [Capsid protein VP4]: Virion.; [Protein 2B]: Host membrane; Peripheral membrane protein.; [Protein 2C]: Host membrane; Single-pass membrane protein.; [Protein 3ABC]: Host membrane; Single-pass membrane protein. Host mitochondrion outer membrane; Single-pass membrane protein.; [Protein 3AB]: Host membrane; Single-pass membrane protein.; [Protein 3A]: Host membrane; Single-pass membrane protein.; [Viral protein genome-linked]: Virion.; [Protease 3C]: Host cytoplasm.; [RNA-directed RNA polymerase 3D-POL]: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Picornaviridae polyprotein family


主站蜘蛛池模板: 亚洲国产精品无码一区二区三区| 成人亚洲a片v一区二区三区蜜臀| 国内熟妇人妻色在线视频 | 国产精品 中文字幕 亚洲 欧美| 亚洲综合伊人久久大杳蕉| 精品人妻一区二区三区浪潮在线| 99久久精品无码一区二区三区| 国内揄拍国产精品人妻门事件 | 狂野欧美性猛xxxx乱大交 | 18禁午夜宅男成年网站| 国产女人高潮叫床视频| 亚洲无线观看国产精品| 最近高清中文在线字幕在线观看1| 吃奶呻吟张开双腿做受在线播放| 亚洲国产av一区二区三区| 人禽无码视频在线观看| 国产在线精品一区二区夜色| 国产午夜高清高清在线观看| 国产三级精品三级| 无码人中文字幕| 色一情一伦一区二区三| 亚洲欧美日韩另类丝袜一区| 少妇的肉体aa片免费| 亚洲中文字幕久久无码精品| 男女啪啪无遮挡免费网站| 亚洲六月丁香六月婷婷| 久久精品无码精品免费专区| 无码中文av有码中文av| 无码国内精品久久人妻蜜桃| 夜夜爱夜鲁夜鲁很鲁| 国产精品一线二线三线| 亚洲欧美日韩中文播放| 国产亚洲日韩一区二区三区| 欧美肥婆姓交大片| 日韩乱码人妻无码中文字幕久久| 久久久久中文伊人久久久| 国产无吗一区二区三区在线欢| 亚洲午夜福利av一区二区无码| 日本两人免费观看的视频| 亚洲一区二区三区国产精品无码| 黑鬼大战白妞高潮喷白浆|