在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human cytomegalovirus Protein UL141 (UL141), partial

  • 中文名稱:
    Recombinant Human cytomegalovirus Protein UL141 (UL141), partial
  • 貨號:
    CSB-MP757720HWW
  • 規格:
    ¥2376
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    UL141
  • Uniprot No.:
  • 種屬:
    Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    56.7 kDa
  • 表達區域:
    37-278aa
  • 氨基酸序列
    DIAEKMWAENYETTSPAPVLVAEGEQVTIPCTVMTHSWPMVSIRARFCRSHDGSDELILDAVKGHRLMNGLQYRLPYATWNFSQLHLGQIFSLTFNVSTDTAGMYECVLRNYSHGLIMQRFVILTQLETLSRPDEPCCTPALGRYSLGDQIWSPTPWRLRNHDCGMYRGFQRNYFYIGRADAEDCWKPACPDEEPDRCWTVIQRYRLPGDCYRSQPHPPKFLPVTPAPPADIDTGMSPWATR
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal hFc1-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Evasion of NK cell killing. Blocks surface expression of PVR which is a ligand for NK cell-activating receptors. Binds human PVR in the endoplasmic reticulum and prevents its maturation and transport to the cell surface. Targets also the natural killer cell activating ligand NECTIN2 for proteasome-mediated degradation. Additionally promotes intracellular retention of TNFRSF10A/TRAIL-R1 and TNFRSF10B/TRAIL-R2 and thus downregulates their cell surface expression.
  • 基因功能參考文獻:
    1. The crystal structure and binding site for viral glycoprotein UL141 reveal an evolutionary immunomodulator targeting two different natural killer (NK) cell signalling pathways, suggesting that the host-receptor interactions are evolutionarily conserved. PMID: 24598754
    2. Human cytomegalovirus UL141 binds to cellular TRAIL-R1 and TRAIL-R2 and protects virus infected cells from NK cell-mediated killing. PMID: 23498957
    3. The authors now show that human cytomegalovirus targets CD112 for proteasome-mediated degradation by 48 h post-infection, thus removing both activating ligands for DNAM-1 from the cell surface during productive infection. PMID: 20410314
  • 亞細胞定位:
    Host endoplasmic reticulum membrane; Single-pass membrane protein.
  • 數據庫鏈接:

    KEGG: vg:3077418



主站蜘蛛池模板: 中文字幕韩国三级理论| 日韩在线一区二区不卡视频| 啪啪激情婷婷久久婷婷色五月| 国产成人精品手机在线观看| 国产午夜激无码av毛片不卡| 伊人蕉久中文字幕无码专区| 国产亚洲精品久久综合阿香| 青青热久免费精品视频| 欧美深度肠交惨叫| 日本高清视频色wwwwww色| 人人做人人爽久久久精品| 暴力强奷在线播放无码| 夜夜躁日日躁狠狠久久av| 中文字幕乱码一区av久久不卡| 日本真人边吃奶边做爽动态图 | 亚洲精品国产福利一区二区| 欧美日韩一本无线码专区| av人摸人人人澡人人超碰下载| 特大巨黑吊xxxx高潮| 久久人妻无码中文字幕第一| 无码日韩人妻av一区免费 | 国产成人精品一区二区秒拍| 日韩在线一区二区三区免费视频| 国内芒果精品自线一区2021| 伊人久久大香线焦av综合影院| 日本被黑人强伦姧人妻完整版| 精品蜜臀av在线天堂| 国产日韩av一区二区三区五区| 夜夜爽日日澡人人添| 国产内射合集颜射| 久久青青草原国产精品最新片 | 思思久久99热只有频精品66| 无码乱码av天堂一区二区| 亚洲色成人www永久网站| 久久亚洲精品成人av二次元| 亚洲精品久久久久午夜福利| 国产精品三级在线观看无码| 国产欧美二区综合| 午夜亚洲国产理论片中文| 亚欧免费无码aⅴ在线观看| 丰满人妻一区二区三区无码av |