在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human cAMP-regulated phosphoprotein 19 (ARPP19)

  • 中文名稱:
    Recombinant Human cAMP-regulated phosphoprotein 19(ARPP19)
  • 貨號:
    CSB-YP348885HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human cAMP-regulated phosphoprotein 19(ARPP19)
  • 貨號:
    CSB-EP348885HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human cAMP-regulated phosphoprotein 19(ARPP19)
  • 貨號:
    CSB-EP348885HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human cAMP-regulated phosphoprotein 19(ARPP19)
  • 貨號:
    CSB-BP348885HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human cAMP-regulated phosphoprotein 19(ARPP19)
  • 貨號:
    CSB-MP348885HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ARPP19
  • Uniprot No.:
  • 別名:
    ARP19; ARP19_HUMAN; ARPP-19; Arpp19; cAMP-regulated phosphoprotein 19
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-112
  • 氨基酸序列
    SAEVPEAAS AEEQKEMEDK VTSPEKAEEA KLKARYPHLG QKPGGSDFLR KRLQKGQKYF DSGDYNMAKA KMKNKQLPTA APDKTEVTGD HIPTPQDLPQ RKPSLVASKL AG
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
  • 基因功能參考文獻:
    1. Together, the results suggest a complex antagonistic interplay between the control of ARPP-16 by MAST3 and PKA that creates a mechanism whereby cAMP mediates PP2A disinhibition. PMID: 28613156
    2. Study showed that ARPP-19 promoted both proliferation and metastasis of human glioma cells and the expression of ARPP-19 and CD147 in high-grade glioma was significantly higher than that in the low-grade glioma. PMID: 27380244
    3. Data show that micrRNA miR-320a directly targets cAMP-regulated phosphoprotein 19 (ARPP-19) and estrogen-related receptor gamma protein (ERRgamma) in breast cancer cell lines. PMID: 25736597
    4. ARPP-19 may play a role in HCC pathogenesis through regulating cell proliferation. PMID: 25547487
    5. ARPP19 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
    6. Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease. PMID: 11771749

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Endosulfine family
  • 數據庫鏈接:

    HGNC: 16967

    OMIM: 605487

    KEGG: hsa:10776

    STRING: 9606.ENSP00000249822

    UniGene: Hs.512908



主站蜘蛛池模板: 18无码粉嫩小泬无套在线观看| 77777亚洲午夜久久多喷| 日本无码人妻精品一区二区蜜桃| 67194熟妇人妻欧美日韩| 国产在线永久视频| 永久免费的av在线电影网无码| 一本久道久久综合狠狠躁av| 久久精品亚洲乱码伦伦中文| а√天堂8资源在线官网| 在线观看免费人成视频色9| 欧美不卡一卡二卡三卡| 国产精品亚洲а∨天堂| 国产午夜精品av一区二区麻豆| 一出一进一爽一粗一大视频| 午夜免费国产体验区免费的| 欧美人与动性xxxxbbbb| 亚洲加勒比无码一区二区| 人妻aⅴ无码一区二区三区| 国产日产欧产精品精品免费| 蜜臀av999无码精品国产专区 | 亚洲色偷偷偷综合网| 色综合天天综合网中文| 欧美精品亚洲精品日韩专区| 日本极品少妇videossexhd| 欧美大屁股xxxx高跟欧美黑人| 无码国内精品久久人妻蜜桃| 亚洲а∨天堂男人色无码| 国产精品18久久久久久麻辣| 亚洲欧美日韩中文播放| 精品无码乱码av| 好了av四色综合无码| 永久免费精品精品永久-夜色 | 六月丁香综合在线视频| 一区二三区在线 | 中国| 午夜不卡av免费| 日本亚洲色大成网站www| 最新网站亚洲人成无码| 欧美两根一起进3p在线观看| 麻豆亚洲一区| 无遮挡午夜男女xx00动态| 大伊香蕉精品视频在线直播 |