在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human adenovirus F serotype 40 Early E1A protein

  • 中文名稱:
    Recombinant Human adenovirus F serotype 40 Early E1A protein
  • 貨號:
    CSB-YP318762HIR
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human adenovirus F serotype 40 Early E1A protein
  • 貨號:
    CSB-EP318762HIR
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human adenovirus F serotype 40 Early E1A protein
  • 貨號:
    CSB-EP318762HIR-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human adenovirus F serotype 40 Early E1A protein
  • 貨號:
    CSB-BP318762HIR
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human adenovirus F serotype 40 Early E1A protein
  • 貨號:
    CSB-MP318762HIR
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Early E1A protein; Early E1A 27 kDa protein
  • 種屬:
    Human adenovirus F serotype 40 (HAdV-40) (Human adenovirus 40)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-249
  • 氨基酸序列
    MRMLPDFFTG NWDDMFQGLL ETEYVFDFPE PSEASEEMSL HDLFDVEVDG FEEDANQEAV DGMFPERLLS EAESAAESGS GDSGVGEELL PVDLDLKCYE DGLPPSDPET DEATEAEEEA AMPTYVNENE NELVLDCPEN PGRGCRACDF HRGTSGNPEA MCALCYMRLT GHCIYSPISD AEGESESGSP EDTDFPHPLT ATPPHGIVRT IPCRVSCRRR PAVECIEDLL EEDPTDEPLN LSLKRPKCS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E1A protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes and of the E2 region of the adenoviral genome. Release of E2F1 leads to the ARF-mediated inhibition of MDM2 and causes TP53/p53 to accumulate because it is not targeted for degradation by MDM2-mediated ubiquitination anymore. This increase in TP53, in turn, would arrest the cell proliferation and direct its death but this effect is counteracted by the viral protein E1B-55K. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Interaction with RBX1 and CUL1 inhibits ubiquitination of the proteins targeted by SCF(FBXW7) ubiquitin ligase complex, and may be linked to unregulated host cell proliferation. The tumorigenesis-restraining activity of E1A may be related to the disruption of the host CtBP-CtIP complex through the CtBP binding motif. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta). Promotes the sumoylation of host ZBED1/hDREF with SUMO1.
  • 亞細胞定位:
    Host nucleus.
  • 蛋白家族:
    Adenoviridae E1A protein family
  • 數據庫鏈接:

    KEGG: vg:2715915



主站蜘蛛池模板: 性人久久久久| 色猫咪av在线观看| 尤物视频在线观看| 久久九九久精品国产日韩经典| 亚洲综合色区无码专区| 久久精品人人爽人人爽| 99精品产国品一二三产区| 欧美自拍亚洲综合丝袜| 国产成人精品日本亚洲语音| 中文字幕在线日亚洲9| 国产精品欧美亚洲韩国日本久久| 国产欧美综合一区二区三区| 久久精品国产99国产精2020丨| 国产在线欧美日韩精品一区| 国产性夜夜春夜夜爽免费下载| 奶头好大狂揉60分钟视频| 久久久精品国产免大香伊| 日韩精品人妻系列无码专区| 日韩在线永久免费播放| 久久亚洲日韩av一区二区三区| 亚洲综合久久一本伊一区| 人妻丰满熟妇av无码区| 狠狠躁夜夜躁人人爽天天不卡| 久久精品国产一区二区三区| 丰满少妇大叫太大太粗| 99热成人精品热久久| 亚洲人成网网址在线看| 亚州少妇无套内射激情视频| 国产精品国语对白露脸在线播放 | 国产色欲色欱www在线| 少妇被黑人4p到惨叫欧美人| 激情航班h版在线观看| 内射后入在线观看一区| 人人妻人人添人人爽欧美一区 | 亚洲乱码在线卡一卡二卡新区豆瓣 | 欧美人与动牲猛交a欧美精品 | 蜜臀aⅴ国产精品久久久国产老师| 亚洲人成人无码www| 日本乱码一区二区三区不卡| 九九精品无码专区免费| 国产精品天干天干综合网|