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Recombinant Human Zinc finger protein 689 (ZNF689)

  • 中文名稱:
    人ZNF689重組蛋白
  • 貨號:
    CSB-YP026953HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人ZNF689重組蛋白
  • 貨號:
    CSB-EP026953HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人ZNF689重組蛋白
  • 貨號:
    CSB-EP026953HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人ZNF689重組蛋白
  • 貨號:
    CSB-BP026953HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人ZNF689重組蛋白
  • 貨號:
    CSB-MP026953HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ZNF689
  • Uniprot No.:
  • 別名:
    ZNF689; Zinc finger protein 689
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-500
  • 氨基酸序列
    MAPPSAPLPA QGPGKARPSR KRGRRPRALK FVDVAVYFSP EEWGCLRPAQ RALYRDVMRE TYGHLGALGC AGPKPALISW LERNTDDWEP AALDPQEYPR GLTVQRKSRT RKKNGEKEVF PPKEAPRKGK RGRRPSKPRL IPRQTSGGPI CPDCGCTFPD HQALESHKCA QNLKKPYPCP DCGRRFSYPS LLVSHRRAHS GECPYVCDQC GKRFSQRKNL SQHQVIHTGE KPYHCPDCGR CFRRSRSLAN HRTTHTGEKP HQCPSCGRRF AYPSLLAIHQ RTHTGEKPYT CLECNRRFRQ RTALVIHQRI HTGEKPYPCP DCERRFSSSS RLVSHRRVHS GERPYACEHC EARFSQRSTL LQHQLLHTGE KPYPCPDCGR AFRRSGSLAI HRSTHTEEKL HACDDCGRRF AYPSLLASHR RVHSGERPYA CDLCSKRFAQ WSHLAQHQLL HTGEKPFPCL ECGRCFRQRW SLAVHKCSPK APNCSPRSAI GGSSQRGNAH
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May be involved in transcriptional regulation.
  • 基因功能參考文獻:
    1. The results indicate that ZNF689 blocks pro-apoptotic signaling by suppressing the Bak/Bax/Bid pathway, resulting in the progression of liver cancer and resistance to 5-FU. ZNF689 may be a promising chemotherapeutic target against liver cancer. PMID: 21624362
    2. overexpressed TIPUH1 may play a role in hepatocarcinogenesis by regulating transcription and/or RNA processing of growth control genes PMID: 16568080
    3. TIPUH1 conferred anchorage independent growth and its knockdown in HCCs resulted in their growth inhibition. Interacts with TIF1beta, hnRNPU, hnRNPF, Nucleolin. May play a role in hepatocarcinogenesis by regulating transcription and/or RNA processing. PMID: 16568080
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Krueppel C2H2-type zinc-finger protein family
  • 數據庫鏈接:

    HGNC: 25173

    KEGG: hsa:115509

    STRING: 9606.ENSP00000287461

    UniGene: Hs.454685



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