在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Zinc finger protein 395 (ZNF395)

Recombinant Human Zinc finger protein 395 (ZNF395)

  • 中文名稱：
    人ZNF395重組蛋白
  • 貨號：
    CSB-YP026718HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ZNF395重組蛋白
  • 貨號：
    CSB-EP026718HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ZNF395重組蛋白
  • 貨號：
    CSB-EP026718HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ZNF395重組蛋白
  • 貨號：
    CSB-BP026718HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ZNF395重組蛋白
  • 貨號：
    CSB-MP026718HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ZNF395
  • Uniprot No.：
  • 別名：
    DKFZp434K1210; HD gene regulatory region binding protein 2; HD gene regulatory region-binding protein 2; HD-regulating factor 2; HDBP-2; HDBP2; HDRF-2; Huntington disease gene regulatory region-binding protein 2; Huntington's disease gene regulatory region binding protein 2; Papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF 1; Papillomavirus-binding factor; PBF; PRF-1; PRF1; PTTG1IP; Si-1-8-14; Zinc finger protein 395; ZN395_HUMAN; znf395
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-513
  • 氨基酸序列
    MASVLSRRLG KRSLLGARVL GPSASEGPSA APPSEPLLEG AAPQPFTTSD DTPCQEQPKE VLKAPSTSGL QQVAFQPGQK VYVWYGGQEC TGLVEQHSWM EGQVTVWLLE QKLQVCCRVE EVWLAELQGP CPQAPPLEPG AQALAYRPVS RNIDVPKRKS DAVEMDEMMA AMVLTSLSCS PVVQSPPGTE ANFSASRAAC DPWKESGDIS DSGSSTTSGH WSGSSGVSTP SPPHPQASPK YLGDAFGSPQ TDHGFETDPD PFLLDEPAPR KRKNSVKVMY KCLWPNCGKV LRSIVGIKRH VKALHLGDTV DSDQFKREED FYYTEVQLKE ESAAAAAAAA AGTPVPGTPT SEPAPTPSMT GLPLSALPPP LHKAQSSGPE HPGPESSLPS GALSKSAPGS FWHIQADHAY QALPSFQIPV SPHIYTSVSW AAAPSAACSL SPVRSRSLSF SEPQQPAPAM KSHLIVTSPP RAQSGARKAR GEAKKCRKVY GIEHRDQWCT ACRWKKACQR FLD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in papillomavirus genes transcription.
  • 基因功能參考文獻：
    1. epigenomic profiling of clear cell renal cell carcinoma (ccRCC) establishes a compendium of somatically altered cis-regulatory elements, uncovering new potential targets including ZNF395. Loss of VHL, a ccRCC signature event, causes pervasive enhancer malfunction, with binding of enhancer-centric HIF2a and recruitment of histone acetyltransferase p300 at preexisting lineage-specific promoter-enhancer complexes PMID: 28893800
    2. The transcriptional activation of CXCL10 and CXCL11 by ZNF395 was abolished after inhibition of IKK by BMS-345541, which increased the stability of ZNF395. ZNF395 encodes at least two motifs that mediate the enhanced degradation of ZNF395 in response to IKK activation. Thus, IKK is required for ZNF395-mediated activation of transcription and enhances its turn-over to keep the activity of ZNF395 low. PMID: 28316371
    3. miR-525-3p promotes liver cancer cell migration and invasion by directly targeting ZNF395. PMID: 24599008
    4. IkBalpha kinase (IKK)-signaling is necessary to allow ZNF395 to activate transcription and simultaneously enhances its proteolytic degradation. PMID: 24086395
    5. Studies indicate that ZNF395 was strongly expressed in adipocytes, and suggest a role for ZNF395 as a modulator of adipogenesis. PMID: 23760207
    6. ZNF395 coordinate the transcriptional regulatory pathway with PPARG2, which may be necessary for the genesis of adipocytes. PMID: 23142027
    7. HDBP1 and HDBP2 are novel transcription factors shuttling between nucleus and cytoplasm and bind to the specific GCCGGCG, which is an essential cis-element for HD gene expression in neuronal cells PMID: 14625278
    8. PBF is a new cellular factor mediating the effects of PI3K/Akt signaling and 14-3-3 on cell growth PMID: 17531190
    9. PBF binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex PMID: 17897615
    10. colocalization of PBF and Scythe/BAT3 in the nucleus might be an important factor for survival of osteosarcoma cells. PMID: 19018758
    11. PBF is an osteosarcoma-associated antigen recognized by autologous cytotoxic T-lymphocyte clone in the context of HLA-B*5502. PMID: 15289353

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 18737

    OMIM: 609494

    KEGG: hsa:55893

    STRING: 9606.ENSP00000340494

    UniGene: Hs.435535



主站蜘蛛池模板： 国产情侣激情在线视频| 男女啪啪永久免费观看网站| 久久精品国产大片免费观看| 亚洲精品国产精品乱码不99| av在线 高清不卡区| 亚洲欧美成人中文日韩电影网站 | 亚洲中文在线精品国产| 99久热re在线精品99re8热视频| 欧美激情一区二区三区在线| av狠狠色超碰丁香婷婷综合久久 | 免费人成又黄又爽的视频| 国产亚洲精品久久久闺蜜| 精品国产第一国产综合精品| 色翁荡息又大又硬又粗又爽| 国精品无码av人妻受辱系| 激情国产一区二区三区四区| 丝袜 亚洲 另类 欧美 变态| 新狼窝色av性久久久久久| 丝袜高跟麻麻浓精受孕人妻| 狼友网精品视频在线观看| 无码熟熟妇丰满人妻porn| 精产一二三产区m553| 亚洲日韩va无码中文字幕| 国产日产欧产精品精品推荐免费| 精品无人区麻豆乱码1区2区| 黄瓜视频在线观看网址| 极品尤物一区二区三区| 精品人妻无码一区二区三区抖音 | 玩弄了裸睡少妇人妻野战| 国产精品免费久久久久软件| 久久丫精品久久丫| 激情亚洲一区国产精品| 老司机性色福利精品视频| 亚洲伊人久久精品影院| 亚洲老妇色熟女老太| 国产一区二区三区免费高清在线播放| 日日碰日日摸夜夜爽无码| 人妻av无码中文专区久久| 精品深夜av无码一区二区老年| 久久国产精品无码hdav| 久久人人97超碰超国产|