在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ZNF395 Antibody

  • 中文名稱:
    ZNF395兔多克隆抗體
  • 貨號:
    CSB-PA026718GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ZNF395
  • 別名:
    DKFZp434K1210 antibody; HD gene regulatory region binding protein 2 antibody; HD gene regulatory region-binding protein 2 antibody; HD-regulating factor 2 antibody; HDBP-2 antibody; HDBP2 antibody; HDRF-2 antibody; Huntington disease gene regulatory region-binding protein 2 antibody; Huntington's disease gene regulatory region binding protein 2 antibody; Papillomavirus regulatory factor 1 antibody; papillomavirus regulatory factor PRF 1 antibody; Papillomavirus-binding factor antibody; PBF antibody; PRF-1 antibody; PRF1 antibody; PTTG1IP antibody; Si-1-8-14 antibody; Zinc finger protein 395 antibody; ZN395_HUMAN antibody; znf395 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ZNF395
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays a role in papillomavirus genes transcription.
  • 基因功能參考文獻:
    1. epigenomic profiling of clear cell renal cell carcinoma (ccRCC) establishes a compendium of somatically altered cis-regulatory elements, uncovering new potential targets including ZNF395. Loss of VHL, a ccRCC signature event, causes pervasive enhancer malfunction, with binding of enhancer-centric HIF2a and recruitment of histone acetyltransferase p300 at preexisting lineage-specific promoter-enhancer complexes PMID: 28893800
    2. The transcriptional activation of CXCL10 and CXCL11 by ZNF395 was abolished after inhibition of IKK by BMS-345541, which increased the stability of ZNF395. ZNF395 encodes at least two motifs that mediate the enhanced degradation of ZNF395 in response to IKK activation. Thus, IKK is required for ZNF395-mediated activation of transcription and enhances its turn-over to keep the activity of ZNF395 low. PMID: 28316371
    3. miR-525-3p promotes liver cancer cell migration and invasion by directly targeting ZNF395. PMID: 24599008
    4. IkBalpha kinase (IKK)-signaling is necessary to allow ZNF395 to activate transcription and simultaneously enhances its proteolytic degradation. PMID: 24086395
    5. Studies indicate that ZNF395 was strongly expressed in adipocytes, and suggest a role for ZNF395 as a modulator of adipogenesis. PMID: 23760207
    6. ZNF395 coordinate the transcriptional regulatory pathway with PPARG2, which may be necessary for the genesis of adipocytes. PMID: 23142027
    7. HDBP1 and HDBP2 are novel transcription factors shuttling between nucleus and cytoplasm and bind to the specific GCCGGCG, which is an essential cis-element for HD gene expression in neuronal cells PMID: 14625278
    8. PBF is a new cellular factor mediating the effects of PI3K/Akt signaling and 14-3-3 on cell growth PMID: 17531190
    9. PBF binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex PMID: 17897615
    10. colocalization of PBF and Scythe/BAT3 in the nucleus might be an important factor for survival of osteosarcoma cells. PMID: 19018758
    11. PBF is an osteosarcoma-associated antigen recognized by autologous cytotoxic T-lymphocyte clone in the context of HLA-B*5502. PMID: 15289353

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm.
  • 組織特異性:
    Widely expressed.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 18737

    OMIM: 609494

    KEGG: hsa:55893

    STRING: 9606.ENSP00000340494

    UniGene: Hs.435535



主站蜘蛛池模板: 欧洲丰满少妇a毛片| 久久综合亚洲色hezyo社区| 国产黄大片在线观看画质优化| 亚洲精品久久久蜜桃 | 国产精品人妻久久毛片高清无卡 | av午夜福利一片免费看久久| 午夜精品国产精品大乳美女| 国产人妻鲁鲁一区二区| 日本又黄又潮娇喘视频| 亚洲精品在看在线观看 | 三上悠亚ssⅰn939无码播放 | 插我舔内射18免费视频| av狼友无码国产在线观看| 国产传媒麻豆剧精品av| 熟妇高潮一区二区三区| 免费又黄又爽又色的视频| 成人欧美一区二区三区黑人免费| 国产情侣大量精品视频| www.一区二区三区在线 | 欧洲| 国产精品视频一区二区三区不卡| 天堂а√中文在线官网| 影音先锋在线亚洲网站| 天天爽天天狠久久久综合麻豆 | h无码动漫在线观看| 天堂av无码大芭蕉伊人av不卡| 无码伊人66久久大杳蕉网站谷歌| 狠狠色狠狠色综合网| 99这里只有精品| 欧美 国产 亚洲视频| 无码少妇一区二区浪潮av| 中文字幕日韩精品有码视频 | 天天躁日日躁狠狠躁免费麻豆| 四房播播开心五月| 久久人人妻人人爽人人爽| 成年无码a√片在线观看| 久久精品免费一区二区| 青青草无码免费一二三区| 国产成人a无码短视频| 99久久99久久精品国产片果冻| 亚洲vs日韩vs欧美vs久久| 国产三级aⅴ在在线观看|