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  4. Recombinant Human Xin actin-binding repeat-containing protein 1 (XIRP1), partial

Recombinant Human Xin actin-binding repeat-containing protein 1 (XIRP1), partial

  • 中文名稱：
    人XIRP1重組蛋白
  • 貨號：
    CSB-YP761658HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人XIRP1重組蛋白
  • 貨號：
    CSB-EP761658HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人XIRP1重組蛋白
  • 貨號：
    CSB-EP761658HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人XIRP1重組蛋白
  • 貨號：
    CSB-BP761658HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人XIRP1重組蛋白
  • 貨號：
    CSB-MP761658HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    XIRP1
  • Uniprot No.：
  • 別名：
    AI415219; Cardiomyopathy-associated protein 1; CMYA1; DKFZp451D042; DKFZp779C1255; DKFZp779C1947; MGC144145; MGC144146; Xin actin-binding repeat-containing protein 1; XIN; Xirp1; XIRP1_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Protects actin filaments from depolymerization.
  • 基因功能參考文獻(xiàn)：
    1. Abnormal CMYA1 expression affects the phosphorylation of Cx43 through the protein kinase c signaling pathway, which is involved in the regulation of gap junction intercellular communication. PMID: 29176328
    2. Aciculin interacts with filamin C and Xin and is essential for myofibril assembly. PMID: 24963132
    3. The strong correlation between the degree of muscle damage and Xin immunoreactivity suggests that Xin may be a suitable outcome measure to evaluate disease progression and treatment effects in clinical trials. PMID: 24225086
    4. We identify the SH3 domains of nebulin and nebulette as novel ligands of proline-rich regions of Xin and XIRP2. PMID: 23985323
    5. Data provide further support that ALS2CL, EPHA3, and CMYA1 are bona-fide tumor-suppressor genes and contribute to the tumorigenesis of HNSCC. PMID: 20657180
    6. Here, we identify Xin, the protein encoded by the human gene 'cardiomyopathy associated 1'(CMYA1) as filamin c binding partner at these specialized structures where the ends of myofibrils are attached to the sarcolemma PMID: 16631741
    7. Data show that in myofibrillar myopathies Xin protein exhibites significant alterations in their localization. PMID: 19151983

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  • 亞細(xì)胞定位：
    Cell junction. Note=Colocalizes with actin stress fibers.
  • 蛋白家族：
    Xin family
  • 組織特異性：
    Isoform A, isoform B and isoform C are expressed in heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14301

    OMIM: 609777

    KEGG: hsa:165904

    STRING: 9606.ENSP00000343140

    UniGene: Hs.447868



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