在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Voltage-gated potassium channel subunit beta-2 (KCNAB2)

  • 中文名稱:
    人KCNAB2重組蛋白
  • 貨號:
    CSB-YP623796HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人KCNAB2重組蛋白
  • 貨號:
    CSB-EP623796HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人KCNAB2重組蛋白
  • 貨號:
    CSB-EP623796HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人KCNAB2重組蛋白
  • 貨號:
    CSB-BP623796HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人KCNAB2重組蛋白
  • 貨號:
    CSB-MP623796HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    KCNAB2
  • Uniprot No.:
  • 別名:
    KCNAB2; KCNA2B; KCNK2Voltage-gated potassium channel subunit beta-2; EC 1.1.1.-; K(+) channel subunit beta-2; Kv-beta-2; hKvbeta2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-367
  • 氨基酸序列
    MYPESTTGSP ARLSLRQTGS PGMIYSTRYG SPKRQLQFYR NLGKSGLRVS CLGLGTWVTF GGQITDEMAE QLMTLAYDNG INLFDTAEVY AAGKAEVVLG NIIKKKGWRR SSLVITTKIF WGGKAETERG LSRKHIIEGL KASLERLQLE YVDVVFANRP DPNTPMEETV RAMTHVINQG MAMYWGTSRW SSMEIMEAYS VARQFNLTPP ICEQAEYHMF QREKVEVQLP ELFHKIGVGA MTWSPLACGI VSGKYDSGIP PYSRASLKGY QWLKDKILSE EGRRQQAKLK ELQAIAERLG CTLPQLAIAW CLRNEGVSSV LLGASNADQL MENIGAIQVL PKLSSSIIHE IDSILGNKPY SKKDYRS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5. Enhances KCNB2 channel activity. Binds NADPH and has NADPH-dependent aldoketoreductase activity. Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro).
  • 基因功能參考文獻:
    1. The results show that KvBeta 2 dysregulation of Kv4.3 is involved in the pathogenesis of Brugada Syndrome. This new finding also expands the list of genes associated with susceptibility to BrS and may contribute to improve molecular diagnosis of this cardiac arrhythmia disorder. PMID: 27287695
    2. Results identified gain and loss of function mutations which lead to increased and decreased potassium currents enhancing AF. PMID: 23264583
    3. Incretin regulation of beta-cell function involves the acetylation of Kv beta2. PMID: 23390957
  • 亞細胞定位:
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Shaker potassium channel beta subunit family
  • 組織特異性:
    Detected in myelinated nerve fibers in the spinal cord, in the juxtaparanodal region of the nodes of Ranvier, but also in the paranodal region. Detected in hippocampus (at protein level). Detected in hippocampus.
  • 數據庫鏈接:

    HGNC: 6229

    OMIM: 601142

    KEGG: hsa:8514

    STRING: 9606.ENSP00000367323

    UniGene: Hs.440497



主站蜘蛛池模板: 成在线人av无码高潮喷水| 全黄性性激高免费视频| 欧美亚洲精品中文字幕乱码| 亚洲va天堂va欧美ⅴa在线| 精品无码乱码av| 67194熟妇在线观看线路1| 久久天天躁狠狠躁夜夜躁2014| 亚洲色成人网站www永久四虎| 亚洲欧美中文日韩v日本| 日本熟妇色一本在线视频| 天天摸夜夜添狠狠添婷婷| 日本一本二本三区免费| 欧美性黑人极品hd另类| 18勿入网站免费永久| 久久精品人人做人人爽| 男女高潮又爽又黄又无遮挡| 国产69精品久久久久久妇女迅雷| 琪琪午夜理论片福利在线观看| 内射精品无码中文字幕| 无码一区二区波多野结衣播放搜索| 两性色午夜视频免费播放 | 老女老肥熟国产在线视频| 久久无码字幕中文久久无码| 亚洲国产美女精品久久久久∴ | 天天燥日日燥| 亚洲欧美综合成人五月天网站| 亚洲人成色77777在线观看大战p| 色两性网欧美| 亚洲精品制服丝袜四区| 人人爽人人澡人人人妻、百度| 青春草在线视频观看| 国产成人综合欧美精品久久| 国产精品亚洲玖玖玖在线观看| 中文无码天天av天天爽| 国产69精品久久久久久久| 久久中文精品无码中文字幕| 日本又黄又爽又色又刺激的视频 | 久久久国产精品亚洲一区| 女人扒下裤让男人桶到爽| 白嫩少妇激情无码| 亚洲人成电影网站色www两男一女|