在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Vesicular glutamate transporter 3 (SLC17A8), partial

  • 中文名稱:
    人SLC17A8重組蛋白
  • 貨號:
    CSB-YP818771HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SLC17A8重組蛋白
  • 貨號:
    CSB-EP818771HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SLC17A8重組蛋白
  • 貨號:
    CSB-EP818771HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SLC17A8重組蛋白
  • 貨號:
    CSB-BP818771HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SLC17A8重組蛋白
  • 貨號:
    CSB-MP818771HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    deafness autosomal dominant 25; DFNA 25; DFNA25; SLC17A8; Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8; Solute carrier family 17 member 8; Vesicular glutamate transporter 3; VGLU3_HUMAN; VGLUT 3; VGluT3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

相關產品

靶點詳情

  • 功能:
    Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
  • 基因功能參考文獻:
    1. Novel pathogenic splicing mutation in SLC17A8 gene identified in a family with hearing loss. PMID: 28647561
    2. A point mutation in VGLUT3 dramatically reduces its expression in synaptic terminals without altering its function. PMID: 28314816
    3. The results of this study identify VGLUT3 as an unexpected regulator of drug abuse. PMID: 26239290
    4. The results from our study suggest that the p.M206Nfs*4 mutation in the SLC17A8 gene is likely a pathogenic mutation that causes autosomal dominant non-syndromic hearing loss. PMID: 26797701
    5. The absence of VGLUT3 in transgenic mice leads to an up-regulation of the midbrain dopamine system and ameliorates motor dysfunction in a model of Parkinson's disease. PMID: 26558771
    6. human vesicular glutamate transporter 3 was cloned, shows 72% identity to both hVGLUT1 and hVGLUT2, and its expression in brain overlaps with hVGLUT1 and hVGLUT2 PMID: 12151341
    7. Docking and homology modeling explain the inhibition of VGLUT3. PMID: 17660252
    8. VGLUT3 immunoreactivity covered only a limited portion of the possible Glu-ergic pathways in the human fetal small intestine. PMID: 18498073
    9. SLC17A8 encodes vesicular glutamate transporter-3, VGLUT3 and its impairment has a role in nonsyndromic deafness DFNA25 and inner hair cell dysfunction PMID: 18674745

    顯示更多

    收起更多

  • 相關疾病:
    Deafness, autosomal dominant, 25 (DFNA25)
  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.
  • 蛋白家族:
    Major facilitator superfamily, Sodium/anion cotransporter family, VGLUT subfamily
  • 組織特異性:
    Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus.
  • 數據庫鏈接:

    HGNC: 20151

    OMIM: 605583

    KEGG: hsa:246213

    STRING: 9606.ENSP00000316909

    UniGene: Hs.116871



主站蜘蛛池模板: 久久综合九色综合97伊人| 波多野结衣av在线观看| 中文字幕精品久久久久人妻| 成人国产片女人爽到高潮| 国产一区二区不卡老阿姨| 熟女俱乐部五十路六十路av| 99热99这里只有高清国产| 欧美乱妇xxxxxbbbbb| 亚洲人成网站18禁止大app| 久久国产精品波多野结衣av| 无码专区人妻系列日韩精品| 亚洲国产成在人网站天堂| 同性女女黄h片在线播放| 欧美35页视频在线观看| 亚洲爆乳少妇无码激情| 久久精品国产精品亚洲| 俄罗斯大荫蒂女人毛茸茸| 亚洲熟少妇在线播放999| 99久久国产成人免费网站| 日本少妇自慰免费完整版| 国产午夜成人久久无码一区二区| 人妻熟女αⅴ一区二区三区| 亚洲人成在线观看网站不卡 | 日韩亚洲中字无码一区二区三区| 亚洲精品少妇高清30p| 8888四色奇米在线观看| 一线二线三线天堂| 欧美网站免费观看在线| 亚洲成av 人片在线观看无码 | 国产99久久久国产精品免费看| 国产在线不卡人成视频| 日韩一区精品视频一区二区| 无码 制服 丝袜 国产 另类| 1000部啪啪未满十八勿入下载| 国产 高潮 抽搐 正在播放| 久久精品国产久精国产爱| 久久久久人妻一区二区三区| 97人妻人人做人碰人人爽| 九九久久精品免费观看| 国产中的精品av一区二区 | 亂倫近親相姦中文字幕|