在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Vesicle-associated membrane protein-associated protein A (VAPA), partial

In Stock
  • 中文名稱:
    Recombinant Human Vesicle-associated membrane protein-associated protein A (VAPA), partial
  • 貨號:
    CSB-EP878947HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    VAMP-A;VAMP-associated protein A;VAP-A;33 kDa VAMP-associated protein;VAP-33
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    32.3 kDa
  • 表達區域:
    2-227aa
  • 氨基酸序列
    ASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking.
  • 基因功能參考文獻:
    1. The effects of sterol manipulation of HuH7 cells on complexes of established sterol-binding Oxysterol-binding protein related proteins with their endoplasmic reticulum receptor, VAMP-associated protein A (VAPA), were examined. PMID: 25681634
    2. phosphorylation of ORP3 controls its association with VAPA. Furthermore, ORP3-VAPA complexes stimulate R-Ras signaling. PMID: 25447204
    3. GPS2 is required for the association of viral NS5A with VAP-A and hepatitis C virus replication. PMID: 24223774
    4. STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the endoplasmic reticulum. PMID: 24105263
    5. phosphorylation of CERT at the FFAT motif-adjacent serine affects its affinity for VAP, which may regulate the inter-organelle trafficking of ceramide in response to the perturbation of cellular sphingomyelin and/or other sphingolipids PMID: 24569996
    6. Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein VAP-33. PMID: 21957124
    7. Data show that the methylated VAPA-APCDD1 DNA in maternal plasma is predominantly derived from the fetus, and this novel fetal epigenetic marker in maternal plasma is useful for the noninvasive detection of fetal trisomy 18. PMID: 21152411
    8. Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies. PMID: 20178991
    9. protein-protein interactions among the various HCV NS proteins and hVAP-33 are important for the formation of HCV replication complex PMID: 15016871
    10. Our results provide suggestive evidence of an association between SNPs in the 3'UTR of the VAPA gene and bipolar disorder. PMID: 18665321
    11. VAP-A is an important regulator both of the subcellular localization of protrudin and of its ability to stimulate neurite outgrowth. PMID: 19289470
    12. GLTP and VAP-A were shown to interact. PMID: 19665998

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cell membrane; Single-pass type IV membrane protein. Cell junction, tight junction. Nucleus membrane.
  • 蛋白家族:
    VAMP-associated protein (VAP) (TC 9.B.17) family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 12648

    OMIM: 605703

    KEGG: hsa:9218

    UniGene: Hs.165195



主站蜘蛛池模板: 婷婷四虎东京热无码群交双飞视频 | 任我爽橹在线精品视频| 国产全是老熟女太爽了| 天天摸天天碰天天添| 久久久久人妻一区二区三区vr| 麻豆ā片免费观看在线看| 又紧又黄的免费视频网站| 中文无码伦av中文字幕| 天天综合天天爱天天做| 精品久久国产综合婷婷五月| 717影院理论午夜伦八戒| 亚洲精品高清无码视频| 大肉大捧一进一出好爽动态图| 亚洲精品偷拍无码不卡av| 131美女爱做视频国产福利| 伦伦影院午夜理论片| 国产69精品久久久久乱码免费| 伊伊人成亚洲综合人网| 真正免费毛片在线播放| 尤物永久网站| 亚洲欧美日韩在线码| 欧美日本特级婬片视频| 国产未成女一区二区| 免费观看美女裸体网站| 男人扒开添女人下部免费视频 | 日本黄页网站免费大全| 夜鲁鲁鲁夜夜综合视频欧美| 丁香婷婷综合久久来来去| 日日摸日日碰夜夜爽无| 久久综合久色欧美综合狠狠| 日韩精品无码一区二区中文字幕| 偷窥村妇洗澡毛毛多| 中文字幕无码精品亚洲资源网久久| 亚洲欧美一区二区三区日产| 国产美女嘘嘘嘘嘘嘘| 夜夜天天噜狠狠爱2019| 亚洲日韩精品a∨片无码| 成人伊人亚洲人综合网站| 午夜香蕉成视频人网站| 国产后入又长又硬| 中文无码熟妇人妻av在线|