在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Vacuolar-sorting protein SNF8 (SNF8)

  • 中文名稱:
    人SNF8重組蛋白
  • 貨號(hào):
    CSB-YP856945HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SNF8重組蛋白
  • 貨號(hào):
    CSB-EP856945HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SNF8重組蛋白
  • 貨號(hào):
    CSB-EP856945HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SNF8重組蛋白
  • 貨號(hào):
    CSB-BP856945HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SNF8重組蛋白
  • 貨號(hào):
    CSB-MP856945HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Dot3; ELL associated protein of 30 kDa; ELL-associated protein of 30 kDa; ESCRT-II complex subunit VPS22; hVps22; snf8; SNF8 ESCRTII complex subunit homolog (S cerevisiae); SNF8_HUMAN; Vacuolar sorting protein SNF8; Vacuolar-sorting protein SNF8; VPS22
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-258
  • 氨基酸序列
    MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF ASKHKQEIRK NPEFRVQFQD MCATIGVDPL ASGKGFWSEM LGVGDFYYEL GVQIIEVCLA LKHRNGGLIT LEELHQQVLK GRGKFAQDVS QDDLIRAIKK LKALGTGFGI IPVGGTYLIQ SVPAELNMDH TVVLQLAEKN GYVTVSEIKA SLKWETERAR QVLEHLLKEG LAWLDLQAPG EAHYWLPALF TDLYSQEITA EEAREALP
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan.
  • 基因功能參考文獻(xiàn):
    1. data describe an unappreciated role for EAP30 in IRF3-dependent innate antiviral response in the nucleus. PMID: 29084253
    2. Taken together, these data suggest an active role for ESCRT-II and CHMP6 in ESCRT-mediated abscission PMID: 25232011
    3. Modulating SNF8 expression levels alters the TRPC6 channel current and can modulate activation of NFAT-mediated transcription downstream of gain-of-function mutant TRPC6. PMID: 23171048
    4. mammalian ESCRTII is made up of hVps25p, hVps22p, and hVps36p and may be redundant, cargo-specific, or not required for protein sorting at the multivesicular body PMID: 16371348
    5. there are probably multiple pathways for protein sorting/multivesicular body vesicle formation in human cells and that human immunodeficiency virus type 1 does not utilize an ESCRT-II-dependent pathway to leave the cell PMID: 16973552
    6. Vps22 has an important role in ligand-induced EGFR and CXCR4 turnover; termination of EGF signaling occurs prior to ESCRT-II engagement PMID: 17714434

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Endosome membrane. Nucleus. Late endosome membrane. Note=Recruited to the endosome membrane to participate in vesicle formation.
  • 蛋白家族:
    SNF8 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 17028

    OMIM: 610904

    KEGG: hsa:11267

    STRING: 9606.ENSP00000421380

    UniGene: Hs.127249



主站蜘蛛池模板: 免费无码鲁丝片一区二区| 无码中文字幕av免费放| 欧美裸体xxxx极品| 两女女百合互慰av赤裸无遮挡| 色噜噜av男人的天堂| 久久精品99国产国产精| 久久久受www免费人成| 丰满日韩放荡少妇无码视频| 午夜免费啪视频观看视频| 国产精品无码无片在线观看| 无码人妻精品一区二区蜜桃网站| av无码东京热亚洲男人的天堂| av无码国产在线观看岛国| 免费人成网站视频在线观看国内 | 无码无套少妇毛多18pxxxx| 熟睡人妻被讨厌的公侵犯深田咏美| 国色精品卡一卡2卡3卡4卡在线| 无码免费中文字幕视频| 国产精品污www一区二区三区| 免费无码av一区二区| 国产精品va尤物在线观看| 色yeye香蕉凹凸视频在线观看| 99久热re在线精品99 6热视频| 国内精品免费久久久久电影院| 久久精品国产精品久久久| 亚洲自偷自拍另类12p| 日日摸日日碰夜夜爽av| 狠狠色综合激情丁香五月| 国产无遮挡a片又黄又爽| 久久精品国产亚洲欧美| 中文字幕av无码一二三区电影| 熟女人妇 成熟妇女系列视频| 国产人妻人伦精品1国产| 97性无码区免费| 少妇真人直播免费视频| 国产看真人毛片爱做a片| 久久久久无码精品国产人妻无码| 国产精品禁18久久久夂久| av在线观看地址| 乱码午夜-极国产极内射| 亚洲成av人片天堂网九九|