在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SNF8 Antibody, Biotin conjugated

SNF8 Antibody, Biotin conjugated

  • 中文名稱：
    SNF8兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA856945LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SNF8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Dot3 antibody; ELL associated protein of 30 kDa antibody; ELL-associated protein of 30 kDa antibody; ESCRT-II complex subunit VPS22 antibody; hVps22 antibody; snf8 antibody; SNF8 ESCRTII complex subunit homolog (S cerevisiae) antibody; SNF8_HUMAN antibody; Vacuolar sorting protein SNF8 antibody; Vacuolar-sorting protein SNF8 antibody; VPS22 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Vacuolar-sorting protein SNF8 protein (1-258AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan.
  • 基因功能參考文獻：
    1. data describe an unappreciated role for EAP30 in IRF3-dependent innate antiviral response in the nucleus. PMID: 29084253
    2. Taken together, these data suggest an active role for ESCRT-II and CHMP6 in ESCRT-mediated abscission PMID: 25232011
    3. Modulating SNF8 expression levels alters the TRPC6 channel current and can modulate activation of NFAT-mediated transcription downstream of gain-of-function mutant TRPC6. PMID: 23171048
    4. mammalian ESCRTII is made up of hVps25p, hVps22p, and hVps36p and may be redundant, cargo-specific, or not required for protein sorting at the multivesicular body PMID: 16371348
    5. there are probably multiple pathways for protein sorting/multivesicular body vesicle formation in human cells and that human immunodeficiency virus type 1 does not utilize an ESCRT-II-dependent pathway to leave the cell PMID: 16973552
    6. Vps22 has an important role in ligand-induced EGFR and CXCR4 turnover; termination of EGF signaling occurs prior to ESCRT-II engagement PMID: 17714434

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endosome membrane. Nucleus. Late endosome membrane. Note=Recruited to the endosome membrane to participate in vesicle formation.
  • 蛋白家族：
    SNF8 family
  • 數據庫鏈接：

    HGNC: 17028

    OMIM: 610904

    KEGG: hsa:11267

    STRING: 9606.ENSP00000421380

    UniGene: Hs.127249



主站蜘蛛池模板： 亚洲人成网线在线播放va蜜芽| 国产高清视频色拍| 久久99精品国产免费观观| 国内精品视频一区二区三区| 色婷婷狠狠久久综合五月| 亚洲 日韩 欧美 成人 在线观看| 九九影院午夜理论片少妇| 日本久久久久久久久久加勒比| 99久久久无码国产精品免费砚床| 日韩丰满少妇无码内射| 免费萌白酱国产一区二区三区| 亚洲中文字幕日产无码成人片| 国产明星裸体xxxx视频| 亚洲国产精品一区二区成人片| 久久精品动漫一区二区三区| 色妺妺av爽爽影院| 国内少妇高潮嗷嗷叫在线播放 | 内射无码专区久久亚洲| 国产嫖妓风韵犹存对白| 国产在线码观看超清无码视频| 自拍偷在线精品自拍偷免费| 麻豆精品一区二区综合av| 亚洲熟妇无码八av在线播放| 9999国产精品欧美久久久久久| 伊人久久精品无码av一区| 欧美激情综合五月色丁香| 久久国内精品自在自线| 精品国产中文字幕在线视频| 无套中出丰满人妻无码| 免费无码黄动漫在线观看| 亚洲欧美综合成人五月天网站| 热re99久久精品国产99热| 日韩中文字幕免费视频| 香蕉蕉亚亚洲aav综合| 久久人人做人人爽人人av| 男女后进式猛烈xx00动态图片| 亚洲人成小说网站色在线| 在线观看国产午夜福利片| 亚洲成av人在线观看网站| 亚洲人av高清无码| 亚洲国产成人久久综合电影|