在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. SNF8 Antibody, Biotin conjugated

SNF8 Antibody, Biotin conjugated

  • 中文名稱：
    SNF8兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA856945LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) SNF8 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Dot3 antibody; ELL associated protein of 30 kDa antibody; ELL-associated protein of 30 kDa antibody; ESCRT-II complex subunit VPS22 antibody; hVps22 antibody; snf8 antibody; SNF8 ESCRTII complex subunit homolog (S cerevisiae) antibody; SNF8_HUMAN antibody; Vacuolar sorting protein SNF8 antibody; Vacuolar-sorting protein SNF8 antibody; VPS22 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Vacuolar-sorting protein SNF8 protein (1-258AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4. Required for the exosomal release of SDCBP, CD63 and syndecan.
  • 基因功能參考文獻：
    1. data describe an unappreciated role for EAP30 in IRF3-dependent innate antiviral response in the nucleus. PMID: 29084253
    2. Taken together, these data suggest an active role for ESCRT-II and CHMP6 in ESCRT-mediated abscission PMID: 25232011
    3. Modulating SNF8 expression levels alters the TRPC6 channel current and can modulate activation of NFAT-mediated transcription downstream of gain-of-function mutant TRPC6. PMID: 23171048
    4. mammalian ESCRTII is made up of hVps25p, hVps22p, and hVps36p and may be redundant, cargo-specific, or not required for protein sorting at the multivesicular body PMID: 16371348
    5. there are probably multiple pathways for protein sorting/multivesicular body vesicle formation in human cells and that human immunodeficiency virus type 1 does not utilize an ESCRT-II-dependent pathway to leave the cell PMID: 16973552
    6. Vps22 has an important role in ligand-induced EGFR and CXCR4 turnover; termination of EGF signaling occurs prior to ESCRT-II engagement PMID: 17714434

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Endosome membrane. Nucleus. Late endosome membrane. Note=Recruited to the endosome membrane to participate in vesicle formation.
  • 蛋白家族：
    SNF8 family
  • 數據庫鏈接：

    HGNC: 17028

    OMIM: 610904

    KEGG: hsa:11267

    STRING: 9606.ENSP00000421380

    UniGene: Hs.127249



主站蜘蛛池模板： 国产av老师丝袜美腿丝袜| 丰满人妻熟妇乱又伦精品| (无码视频)在线观看| 男男女女爽爽爽免费视频| 好吊射视频988gaocom| 大胸少妇午夜三级| 久久精品99国产国产精| 久久精品免视看国产成人明星| 国产午夜a理论毛片| 国产午夜片无码区在线观看| 无码精品人妻一区二区三区影院 | 噜噜色综合天天综合网mp3| 人妻少妇精品久久| 99久久久国产精品无码免费| 成人免费b2b网站大全在线| 国产视频亚洲精品视频| 日韩欧美国产aⅴ另类| 国产精品综合色区在线观看| 最新成年女人毛片免费基地| 日韩人妻无码精品专区906188 | av人摸人人人澡人人超碰妓女| 国产老熟女网站| 香蕉噜噜噜噜私人影院 | 国产人成高清在线视频99最全资源| 在线观看片a免费不卡观看| 亚洲精品自在在线观看| 色婷婷五月综合久久| 无码人妻少妇久久中文字幕蜜桃 | 色爽黄1000部免费软件下载| 精品av国产一二三四区| 欧美老肥熟妇多毛xxxxx| 国内精品久久久久影院一蜜桃| 欧洲熟妇牲交| 中国内射xxxx6981少妇| 国产成人一区二区不卡免费视频| 白又丰满大屁股bbbbb| 亚洲国产午夜精华无码福利| 亚洲精品无码专区在线播放 | 18禁男女爽爽爽午夜网站免费| 在线观看国产成人av天堂| 国产精品白丝av网站|