在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human V-type immunoglobulin domain-containing suppressor of T-cell activation (VSIR), partial,Biotinylated

  • 中文名稱:
    人VSIR重組蛋白
  • 貨號:
    CSB-MP884484HU-B
  • 規格:
    ¥1860
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
  • Uniprot No.:
  • 別名:
    Platelet receptor Gi24;Stress-induced secreted protein-1;Sisp-1;V-set domain-containing immunoregulatory receptor;V-set immunoregulatory receptor
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    Mammalian cell
  • 分子量:
    23.0 kDa
  • 表達區域:
    33-194aa
  • 氨基酸序列
    FKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQESENITAA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 10xHis-Avi-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation.
  • 基因功能參考文獻:
    1. Data indicate that VISTA is predominantly expressed and up-regulated in the high-density infiltrated immune cells but minimal in pancreatic cancerous cells. PMID: 29771768
    2. High VISTA expression is associated with colorectal carcinoma. PMID: 30128738
    3. VISTA expression supports immune-complex inflammation in collagen antibody-induced arthritis and VISTA is expressed in human synovium PMID: 29216931
    4. This study is the first to describe the expression of VISTA-expressing lymphocytes in melanoma samples and in the context of acquired resistance to immune checkpoint inhibitors PMID: 28776578
    5. Taken together, the results indicated that the VISTA high and CD8 low group, as an immunosuppressive subgroup, might be associated with a poor prognosis in primary OSCC. These findings indicated that VISTA might be a potential immunotherapeutic target in OSCC treatment. PMID: 28236118
    6. this review describes the functions of VISTA in the context of cancer immunotherapy PMID: 28258694
    7. overexpression of the newly described co-stimulatory molecule, PD1 homologue (PD-1H) in human monocyte/macrophages is sufficient to induce spontaneous secretion of multiple cytokines. PMID: 25279955
    8. p53-induced expression of DD1alpha prevents persistence of cell corpses and ensures efficient generation of precise immune responses in mice. PMID: 26228159
    9. Results suggest that GI24 contributes to tumor-invasive growth in the collagen matrix by augmenting cell surface MT1-MMP. PMID: 20666777

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Expressed in spleen. Detected on a number of myeloid cells including CD11b monocytes, CD66b+ neutrophils, at low levels on CD4+ and CD8+ T-cells, and in a subset of NK cells. Not detected on B cells (at protein level). Expressed at high levels in placenta
  • 數據庫鏈接:

    HGNC: 30085

    OMIM: 615608

    KEGG: hsa:64115

    STRING: 9606.ENSP00000378409

    UniGene: Hs.47382



主站蜘蛛池模板: 精品国产乱码久久久久久口爆| 我和亲妺妺乱的性视频| 日本午夜免费福利视频| 日本高清视频网站www| а√天堂www在线а√天堂资源| 天天澡日日澡狠狠欧美老妇 | 成人国产精品秘片多多| 麻豆国产一区二区三区四区| 国产女主播喷水视频在线观看 | 七月丁香五月婷婷首页| 精品国产在天天在线观看| 中文字幕人妻无码一夲道| 欧美成人免费一区二区| 青青爽无码视频在线观看| 久久婷婷五月综合色首页| 国产成人亚洲综合无码品善网| 久久婷婷五月综合鬼色| 少妇粉嫩小泬白浆流出| 精品无码中文视频在线观看| 国产一区二区三区 韩国女主播| 国产精品乱子伦xxxx| 日本动漫瀑乳h动漫啪啪免费| 精品蜜臀久久久久99网站| 欧美丰满老熟妇xxxxx性| 国产亚洲综合网曝门系列| 亚洲卡一卡二卡三新区乱码| 久久久免费无码成人影片 | 一本大道大臿蕉视频无码| 99久久99久久久精品齐齐| 国产乱码精品一品二品| 国产99视频精品免视看9| 波多野无码黑人在线播放| 好男人在线社区www在线影院| 欧美刺激性大交| 九九九国产精品成人免费视频| 国产精品高潮露脸在线观看| 真实国产乱子伦对白在线播放| ass日本丰满熟妇pics| 成av人电影在线观看| 菠萝菠萝蜜午夜视频在线播放观看| 国产99视频精品免费视看6|