在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2)

In Stock
  • 中文名稱:
    人UBE2V2重組蛋白
  • 貨號:
    CSB-EP025484HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    UBE2V2
  • Uniprot No.:
  • 別名:
    1 alpha 25 dihydroxyvitamin D3 inducible; DDVit 1; DDVIT1; EDAF-1; EDAF1; EDPF-1; EDPF1; Enterocyte differentiation associated factor EDAF 1; Enterocyte differentiation promoting factor; Enterocyte differentiation-associated factor 1; Enterocyte differentiation-promoting factor 1; Methyl methanesulfonate sensitive 2; MMS 2; MMS2; MMS2 homolog; UB2V2_HUMAN; UBE2V 2; UBE2V2; Ubiquitin conjugating enzyme E2 variant 2; Ubiquitin conjugating enzyme E2v2; Ubiquitin-conjugating enzyme E2 variant 2; UEV 2; UEV2; Vitamin D3 inducible protein; Vitamin D3-inducible protein
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    32.2kDa
  • 表達區域:
    2-145aa
  • 氨基酸序列
    AVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
  • 基因功能參考文獻:
    1. Functional analysis of selected regulated proteins revealed that knockdown of HNRPD, PHB2 and UB2V2 can increase HCMV replication, while knockdown of A4 and KSRP resulted in decreased HCMV replication. PMID: 25910425
    2. suppression of hMMS2 reverses L-OHP tolerance in differentiated human colorectal carcinoma cells by promoting apoptosis PMID: 24846979
    3. UBE2v2 signalling through PCNA ubiquitination is not required for immunoglobulin diversification in DT40 cells. PMID: 15725630
    4. Insight into the influence of protein dynamics on the affinity of ubiquitin for Mms2. PMID: 15952783
    5. Mms2 physical association with ubiquitin is correlated with its ability to promote Lys63-linked ubiquitin chain assembly PMID: 17964296
    6. These results point to a high level of redundancy in the DNA damage tolerance pathway and suggest the existence of another hMMS2 variant (hMMSv) or complex that can compensate for its loss. PMID: 18284681

    顯示更多

    收起更多

  • 蛋白家族:
    Ubiquitin-conjugating enzyme family
  • 組織特異性:
    Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues.
  • 數據庫鏈接:

    HGNC: 12495

    OMIM: 603001

    KEGG: hsa:7336

    STRING: 9606.ENSP00000428209

    UniGene: Hs.491695



主站蜘蛛池模板: 四虎精品成人免费视频| 色优久久久久综合网鬼色| 国产成人无码一区二区三区| 欧美xxxx做受欧美| 日韩一本之道一区中文字幕| 久久久久免费看成人影片| 亚洲中文字幕乱码一区| 韩日综合成人中文字幕| 内射极品少妇xxxxxhd | 在线人人车操人人看视频| 欧美最猛性xxxxx大叫| 大香网伊人久久综合网2018| 精品久久人妻av中文字幕| 亚洲精品第一国产综合亚av| 亚洲精品无码久久毛片 | 久久久国产乱子伦精品作者| 97超级碰碰人妻中文字幕| 特黄做受又粗又长又大又硬| 777米奇色狠狠俺去啦奇米77| 男人j进入女人j内部免费网站| 精品无人区卡一卡二卡三乱码| 9999国产精品欧美久久久久久| 自拍偷在线精品自拍偷免费| 精品久久国产字幕高潮| 亚洲成av人片在一线观看| 亚洲区小说区激情区图片区| 国产乱子伦一区二区三区=| 国产精品免费久久久久影院 | 性高朝久久久久久久| 美女裸体视频永久免费| 拍国产乱人伦偷精品视频| 亚洲男人成人性天堂网站| 欧美人与动牲猛交a欧美精品| 国产精品久久久久av| 极品少妇被猛得白浆直喷白浆小说| 国产无遮挡又黄又爽免费视频| 十八禁视频网站在线观看| 国产一区二区三区精品av| 亚洲国产福利一区二区三区| 一区二区乱子伦在线播放| 日本国产网曝视频在线观看|