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Recombinant Human UDP-glucose:glycoprotein glucosyltransferase 2 (UGGT2), partial

  • 中文名稱:
    人UGGT2重組蛋白
  • 貨號:
    CSB-YP865182HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人UGGT2重組蛋白
  • 貨號:
    CSB-EP865182HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人UGGT2重組蛋白
  • 貨號:
    CSB-EP865182HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人UGGT2重組蛋白
  • 貨號:
    CSB-BP865182HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人UGGT2重組蛋白
  • 貨號:
    CSB-MP865182HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    UGGT2; UGCGL2; UGT2UDP-glucose:glycoprotein glucosyltransferase 2; UGT2; hUGT2; EC 2.4.1.-; UDP--Glc:glycoprotein glucosyltransferase 2; UDP-glucose ceramide glucosyltransferase-like 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
  • 基因功能參考文獻:
    1. In this study, we aimed to clarify the contribution of the noncatalytic domains by comparing activities of truncated forms of recombinant HUGT1/HUGT2 and HUGT1/HUGT2 chimeras with full-length enzymes. PMID: 27496766
    2. The glucosyltransferase activity of UGGT2 has been lacking, leaving it unclear as to whether it has any function in the glycoprotein folding process. PMID: 24415556
    3. HUGT2 cannot activate the catalytic domain of UDP-glucose: glycoprotein glucosyltransferase I PMID: 12913004
  • 亞細胞定位:
    Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.
  • 蛋白家族:
    Glycosyltransferase 8 family
  • 組織特異性:
    Higher levels in kidney, pancreas, heart, and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 15664

    OMIM: 605898

    KEGG: hsa:55757

    STRING: 9606.ENSP00000365938

    UniGene: Hs.193226



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