Recombinant Human Transmembrane protein 205 (TMEM205), partial

中文名稱：

人TMEM205重組蛋白
貨號：

CSB-YP023799HU1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人TMEM205重組蛋白
貨號：

CSB-EP023799HU1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人TMEM205重組蛋白
貨號：

CSB-EP023799HU1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TMEM205重組蛋白
貨號：

CSB-BP023799HU1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人TMEM205重組蛋白
貨號：

CSB-MP023799HU1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
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靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

TMEM205
Uniprot No.：

Q6UW68
別名：

TMEM205; UNQ501/PRO1018; Transmembrane protein 205
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
基因功能參考文獻(xiàn)：
1. The genetic polymorphisms in OCT2, AQP2, AQP9 and TMEM205 may contribute to chemotherapy response in lung cancer patients. PMID: 24643204
2. Results indicate that a novel mechanism for cisplatin resistance is mediated by TMEM205 overexpression. PMID: 20589834
亞細(xì)胞定位：

Membrane; Multi-pass membrane protein. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
蛋白家族：

TMEM205 family
組織特異性：

Widely expressed with highest levels in pancreas, followed by adrenal gland, thyroid, liver, mammary gland, prostate, kidney, and retina; lowest levels in skeletal muscle. Overexpressed in cisplatin-resistant cancer cells (at protein level).
數(shù)據(jù)庫鏈接：

HGNC: 29631

OMIM: 613771

KEGG: hsa:374882

STRING: 9606.ENSP00000346954

UniGene: Hs.737060