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Your Good Partner in Biology Research

TMEM205 Antibody, Biotin conjugated

  • 中文名稱(chēng):
    TMEM205兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA023799LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) TMEM205 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMEM205
  • 別名:
    TMEM205; UNQ501/PRO1018; Transmembrane protein 205
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane protein 205 protein (104-153AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.
  • 基因功能參考文獻(xiàn):
    1. The genetic polymorphisms in OCT2, AQP2, AQP9 and TMEM205 may contribute to chemotherapy response in lung cancer patients. PMID: 24643204
    2. Results indicate that a novel mechanism for cisplatin resistance is mediated by TMEM205 overexpression. PMID: 20589834
  • 亞細(xì)胞定位:
    Membrane; Multi-pass membrane protein. Note=Located on cell surface microvilli. In cancer cells, transition in subcellular location from cell surface to intracellular regions correlates the progression of cisplatin resistance.
  • 蛋白家族:
    TMEM205 family
  • 組織特異性:
    Widely expressed with highest levels in pancreas, followed by adrenal gland, thyroid, liver, mammary gland, prostate, kidney, and retina; lowest levels in skeletal muscle. Overexpressed in cisplatin-resistant cancer cells (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 29631

    OMIM: 613771

    KEGG: hsa:374882

    STRING: 9606.ENSP00000346954

    UniGene: Hs.737060



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