在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Translation initiation factor eIF-2B subunit delta (EIF2B4)

Recombinant Human Translation initiation factor eIF-2B subunit delta (EIF2B4)

  • 中文名稱：
    人EIF2B4重組蛋白
  • 貨號：
    CSB-YP887053HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EIF2B4重組蛋白
  • 貨號：
    CSB-EP887053HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EIF2B4重組蛋白
  • 貨號：
    CSB-EP887053HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EIF2B4重組蛋白
  • 貨號：
    CSB-BP887053HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EIF2B4重組蛋白
  • 貨號：
    CSB-MP887053HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EIF2B4
  • Uniprot No.：
  • 別名：
    EI2BD_HUMAN; EIF 2B; eIF 2B GDP GTP exchange factor subunit delta; eIF-2B GDP-GTP exchange factor subunit delta; Eif2b4; EIF2Bdelta; eukaryotic translation initiation factor 2B subunit 4; Translation initiation factor eIF-2B subunit delta
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-523
  • 氨基酸序列
    AAVAVAVRE DSGSGMKAEL PPGPGAVGRE MTKEEKLQLR KEKKQQKKKR KEEKGAEPET GSAVSAAQCQ VGPTRELPES GIQLGTPREK VPAGRSKAEL RAERRAKQEA ERALKQARKG EQGGPPPKAS PSTAGETPSG VKRLPEYPQV DDLLLRRLVK KPERQQVPTR KDYGSKVSLF SHLPQYSRQN SLTQFMSIPS SVIHPAMVRL GLQYSQGLVS GSNARCIALL RALQQVIQDY TTPPNEELSR DLVNKLKPYM SFLTQCRPLS ASMHNAIKFL NKEITSVGSS KREEEAKSEL RAAIDRYVQE KIVLAAQAIS RFAYQKISNG DVILVYGCSS LVSRILQEAW TEGRRFRVVV VDSRPWLEGR HTLRSLVHAG VPASYLLIPA ASYVLPEVSK VLLGAHALLA NGSVMSRVGT AQLALVARAH NVPVLVCCET YKFCERVQTD AFVSNELDDP DDLQCKRGEH VALANWQNHA SLRLLNLVYD VTPPELVDLV ITELGMIPCS SVPVVLRVKS SDQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
  • 基因功能參考文獻：
    1. A novel missense mutation within EIF2B4 is associated with vanishing white matter disease. PMID: 25600065
    2. demonstrate that DAP5 associates with eIF2beta and eIF4AI to stimulate IRES-dependent translation of cellular mRNAs PMID: 25779044
    3. The functional effects of selected vanishing white matter disease mutations in EIF2B2-5 by coexpressing mutated and wild-type subunits in human cells. PMID: 21560189
    4. analysis of developmental splicing deregulation in leukodystrophies related to EIF2B mutations PMID: 22737209
    5. A mutation .626G>A [p.Arg209Gln] in exon 7 and c.1399C>T [p.Arg467Trp] in exon 13 of the EIF2B4-Gens. PMID: 21503715
    6. Data demonstrate that cellular response resulting from eIF2alpha phosphorylation is attenuated in several cancer cell lines, and correlates with the expression of a specific isoform of a regulatory eIF2B subunit, eIF2Bdelta variant 1 (V1). PMID: 20709751
    7. These results validate the measurement of eIF2B GEF activity in patients' transformed-lymphocytes as an important tool for the diagnosis of eIF2B-related disorders. PMID: 20016818
    8. A unique EIF2B mutation spectrum in Chinese Vanishing white matter patients was shown. PMID: 19158808
    9. Mutation in EIF2B4 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy. PMID: 12707859
    10. We report for the first time that in vitro fertilization and embryo transfer can lead to a successful procreation in patients with OLD related to EIF2B mutations. PMID: 18005052
    11. This study describe here a case suggestive of ovarioleukodistrophy carrying no eIF2B mutations. PMID: 18061208
    12. A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of EIF-2B, is reported. PMID: 18160716
    13. Study reports 9 novel mutations in EIF2B genes in 8 patients, increasing number of known mutations to more than 120. Using homology modeling, analyzed the impact of novel mutations on the 5 subunits of eIF2B protein (alpha, beta, gamma, delta, epsilon) PMID: 18263758
    14. The authors suspected VWM and sequenced the genes EIF2B1-5, which revealed one heterozygous mutation in EIF2B4. PMID: 18330844
    15. We describe the first Chinese patient with typical clinical and radiological features genetically confirmed to have vanishing white matter disease for a mutation in EIF2B4. PMID: 18539998

    顯示更多

    收起更多

  • 相關疾病：
    Leukodystrophy with vanishing white matter (VWM)
  • 蛋白家族：
    EIF-2B alpha/beta/delta subunits family
  • 數據庫鏈接：

    HGNC: 3260

    OMIM: 603896

    KEGG: hsa:8890

    STRING: 9606.ENSP00000394869

    UniGene: Hs.169474



主站蜘蛛池模板： 国产精品久久人妻互换| 2021国产精品一卡2卡三卡4卡| 国产av一区二区精品凹凸| 日本无遮挡吸乳呻吟视频| 成人av一本不卡二卡| 精品无码久久久久久久久久| 免费精品国产人妻国语| 亚洲精品一区二区三区新线路| 影音先锋在线亚洲网站| 成年黄页网站大全免费无码| 国产顶级熟妇高潮xxxxx| 久久综合给合综合久久| 免费无码成人片| 日本精品中文字幕在线播放| 女人与公拘交酡全过程| 又紧又黄的免费视频网站| 人妻丰满熟妇av无码区app| 超碰人人超碰人人| 久久夜色撩人精品国产小说| 成人a片产无码免费视频在线观看| 国产免费高清69式视频在线观看 | 五月天中文字幕mv在线| 无码av高潮抽搐流白浆| 忘忧草日本在线www| 久久免费精品国产72精品九九| 国产精品免费大片| 国产suv精品一区二区五| 亚洲国产欧美一区二区好看电影| 亚洲爆乳aaa无码专区| 日韩夜夜高潮夜夜爽无码| 四虎国产精品永久在线| 97影院理论午夜伦不卡| 亚洲国产欧美在线观看片不卡| 无码孕妇孕交在线观看| 丰满人妻熟妇乱又伦精品视| 亚洲国产精品无码久久一线| 国产三级视频在线播放线观看| 中文字幕人成无码人妻综合社区| 九九视频在线观看视频6| 上司人妻互换hd无码| 日本一卡二卡3卡四卡网站精品 |