在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transcription factor Dp family member 3 (TFDP3)

  • 中文名稱:
    人TFDP3重組蛋白
  • 貨號:
    CSB-YP702134HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TFDP3重組蛋白
  • 貨號:
    CSB-EP702134HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TFDP3重組蛋白
  • 貨號:
    CSB-EP702134HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TFDP3重組蛋白
  • 貨號:
    CSB-BP702134HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TFDP3重組蛋白
  • 貨號:
    CSB-MP702134HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TFDP3
  • Uniprot No.:
  • 別名:
    Cancer/testis antigen 30; CT30; DP4; E2F like protein; E2F-like; HCA661; Hepatocellular carcinoma-associated antigen 661; TFDP3; TFDP3_HUMAN; Transcription factor Dp family member 3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-405
  • 氨基酸序列
    MAKYVSLTEA NEELKVLMDE NQTSRPVAVH TSTVNPLGKQ LLPKTFGQSS VNIDQQVVIG MPQRPAASNI PVVGSPNPPS THFASQNQHS YSSPPWAGQH NRKGEKNGMG LCRLSMKVWE TVQRKGTTSC QEVVGELVAK FRAASNHASP NESAYDVKNI KRRTYDALNV LMAMNIISRE KKKIKWIGLT TNSAQNCQNL RVERQKRLER IKQKQSELQQ LILQQIAFKN LVLRNQYVEE QVSQRPLPNS VIHVPFIIIS SSKKTVINCS ISDDKSEYLF KFNSSFEIHD DTEVLMWMGM TFGLESGSCS AEDLKMARNL VPKALEPYVT EMAQGTFGGV FTTAGSRSNG TWLSASDLTN IAIGMLATSS GGSQYSGSRV ETPAVEEEEE EDNNDDDLSE NDEDD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.
  • 基因功能參考文獻:
    1. Authors established a preclinical model of resistance to induction therapy to examine the functional relevance of TFDP3 to chemoresistance in MRD derived from Jurkat/E6-1. PMID: 27902457
    2. TFDP3 can bind to E2F1 molecule to form E2F/TFDP3 complex; and the localizations of TFDP3 and E2F1 molecules and the co-localization were different in different phases of cell cycle in the nucleus and cytoplasm, which indicated that the E2F/TFDP3 complex involved in the process of regulating the cell cycle. PMID: 28797103
    3. data highlight that TFDP3 is expressed in breast cancer, that it is a member of the cancer-testis antigen family and that it functions as a regulator in epithelial-mesenchymal transition PMID: 28114432
    4. TFDP3 was highly expressed in cancer tissues including prostate cancer tissues.TFDP3 was expressed in coordination with E2F1 in most prostate cancer tissues. PMID: 24406621
    5. Data gathered from cell lines, tumorigenicity studies, and primary hepatocellular carcinoma samples demonstrate a negative role of HIF-2alpha in tumors, which is mediated by the TFDP3/E2F1 pathway. PMID: 23212661
    6. Data show that TFDP3 upregulates the expression of autophagy gene LC3B and inhibits E2F1-induced apoptosis, and may play an important role in prostate cancer. PMID: 22482402
    7. DP-4 downregulating E2F-1 activity and contributes to a new pRb-independent mechanism for regulating cell cycle progression. PMID: 20559320
    8. TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2F PMID: 17062573

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.
  • 蛋白家族:
    E2F/DP family
  • 組織特異性:
    Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.
  • 數據庫鏈接:

    HGNC: 24603

    OMIM: 300772

    KEGG: hsa:51270

    STRING: 9606.ENSP00000385461

    UniGene: Hs.142908



主站蜘蛛池模板: 人禽杂交18禁网站免费| 狠狠躁18三区二区一区ai明星| 少妇高潮一区二区三区99 | 男阳茎进女阳道视频大全 | 国产成人亚洲高清一区| 国产内射一区亚洲| 特级西西人体444www高清大胆| 精品国产sm最大网免费站| 国产人成无码视频在线| 精品无码久久久久国产电影| 国产白嫩护士被弄高潮| 成人毛片无码一区二区三区| 人人妻人人澡人人爽国产| 日韩人妻不卡一区二区三区| 粉嫩小泬无遮挡久久久久久| 久久综合久久久久88| 色资源av中文无码先锋| 国内精品乱码卡一卡2卡三卡新区| 亚洲国产中文在线视频| 无码福利日韩神码福利片| 久久伊人精品波多野结衣| 午夜福利视频一区二区手机免费看| 日本一卡2卡3卡四卡精品网站| 久久久性色精品国产免费观看| 色九月亚洲综合网| 久久www免费人成_看片老司机| 欧美性猛交ⅹxxx乱大交妖精| 亚洲精品国精品久久99热| 欧美乱妇xxxxxbbbbb| 久久久久麻豆v国产精华液好用吗| 国产乱妇乱子视频在播放| 国产手机在线亚洲精品观看 | 欧美疯狂做受xxxxx高潮| 亚洲a成人无码网站在线| 色欲aⅴ 无码| 国产口爆吞精在线视频2020版| 亚洲日韩久热中文字幕| 欧美日产欧美日产国产精品| 精品久久久久久久中文字幕| 精品久久亚洲中文无码| 国产一区二区三区精品av|