在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TFDP3 Antibody, Biotin conjugated

  • 中文名稱:
    TFDP3兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA702134LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TFDP3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TFDP3
  • 別名:
    Cancer/testis antigen 30 antibody; CT30 antibody; DP4 antibody; E2F like protein antibody; E2F-like antibody; HCA661 antibody; Hepatocellular carcinoma-associated antigen 661 antibody; TFDP3 antibody; TFDP3_HUMAN antibody; Transcription factor Dp family member 3 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Transcription factor Dp family member 3 protein (61-196AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.
  • 基因功能參考文獻(xiàn):
    1. Authors established a preclinical model of resistance to induction therapy to examine the functional relevance of TFDP3 to chemoresistance in MRD derived from Jurkat/E6-1. PMID: 27902457
    2. TFDP3 can bind to E2F1 molecule to form E2F/TFDP3 complex; and the localizations of TFDP3 and E2F1 molecules and the co-localization were different in different phases of cell cycle in the nucleus and cytoplasm, which indicated that the E2F/TFDP3 complex involved in the process of regulating the cell cycle. PMID: 28797103
    3. data highlight that TFDP3 is expressed in breast cancer, that it is a member of the cancer-testis antigen family and that it functions as a regulator in epithelial-mesenchymal transition PMID: 28114432
    4. TFDP3 was highly expressed in cancer tissues including prostate cancer tissues.TFDP3 was expressed in coordination with E2F1 in most prostate cancer tissues. PMID: 24406621
    5. Data gathered from cell lines, tumorigenicity studies, and primary hepatocellular carcinoma samples demonstrate a negative role of HIF-2alpha in tumors, which is mediated by the TFDP3/E2F1 pathway. PMID: 23212661
    6. Data show that TFDP3 upregulates the expression of autophagy gene LC3B and inhibits E2F1-induced apoptosis, and may play an important role in prostate cancer. PMID: 22482402
    7. DP-4 downregulating E2F-1 activity and contributes to a new pRb-independent mechanism for regulating cell cycle progression. PMID: 20559320
    8. TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2F PMID: 17062573

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.
  • 蛋白家族:
    E2F/DP family
  • 組織特異性:
    Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24603

    OMIM: 300772

    KEGG: hsa:51270

    STRING: 9606.ENSP00000385461

    UniGene: Hs.142908



主站蜘蛛池模板: 午夜射精日本三级| 亚洲人成人77777网站| 337p日本欧洲亚洲大胆裸体艺术| 日本午夜免费福利视频| 亚洲熟女久久色| 一区二区视频日韩免费| 亚洲色大成网站www久久九九| 国产熟女一区二区三区四区五区 | 人人爽人人澡人人高潮| 欧美高潮喷水大叫| 欧美va久久久噜噜噜久久| 欧洲精品码一区二区三区免费看 | 国产69囗曝吞精在线视频| 蜜臀视频一区二区在线播放| 亚洲一区二区三区四区五区六区| 97精品一区二区视频在线观看| 亚洲色大网站www永久网站| 欧美黑人巨大xxxxx视频| 中文字幕日韩精品有码视频| 亚洲永久网址在线观看| 成年无码av片在线免缓冲| 免费看又色又爽又黄的国产软件| 国产又粗又猛又大爽又黄| 欧美大胆少妇bbw| 熟女俱乐部五十路六十路av| 无码8090精品久久一区| 露脸内射熟女--69xx| 亚洲日韩中文第一精品| 99国产精品久久久蜜芽| 六月丁香亚洲综合在线视频| 国产又爽又黄又无遮挡的激情视频| 青草青草久热精品视频在线观看 | 国内精品久久久久影院免费 | 免费啪视频在线观看视频日本| 无码国产精品一区二区免费16| 国产97在线 | 免费| 亚洲大成色www永久网站动图| 亚洲国产欧美在线人成aaaa| 老太婆性杂交欧美肥老太| 久久青青草原国产毛片| 真实国产乱子伦对白在线播放|