在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Trans-2-enoyl-CoA reductase, mitochondrial (MECR)

  • 中文名稱:
    人MECR重組蛋白
  • 貨號:
    CSB-YP887132HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MECR重組蛋白
  • 貨號:
    CSB-EP887132HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人MECR重組蛋白
  • 貨號:
    CSB-EP887132HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MECR重組蛋白
  • 貨號:
    CSB-BP887132HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MECR重組蛋白
  • 貨號:
    CSB-MP887132HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MECR
  • Uniprot No.:
  • 別名:
    AI195831; CGI 63; FASN2B; Homolog of yeast 2 enoyl thioester reductase; HsNrbf-1; HsNrbf1; mecr; MECR_HUMAN; Mitochondrial 2 enoyl thioester reductase; mitochondrial; NRBF 1; NRBF-1; NRBF1; Nuclear receptor binding factor 1; Nuclear receptor-binding factor 1; OTTMUSP00000009996; RP23-13A13.1; Trans 2 enoyl CoA reductase; mitochondrial; Trans-2-enoyl-CoA reductase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    54-373
  • 氨基酸序列
    PAKVVEL KNLELAAVRG SDVRVKMLAA PINPSDINMI QGNYGFLPEL PAVGGNEGVA QVVAVGSNVT GLKPGDWVIP ANAGLGTWRT EAVFSEEALI QVPSDIPLQS AATLGVNPCT AYRMLMDFEQ LQPGDSVIQN ASNSGVGQAV IQIAAALGLR TINVVRDRPD IQKLSDRLKS LGAEHVITEE ELRRPEMKNF FKDMPQPRLA LNCVGGKSST ELLRQLARGG TMVTYGGMAK QPVVASVSLL IFKDLKLRGF WLSQWKKDHS PDQFKELILT LCDLIRRGQL TAPACSQVPL QDYQSALEAS MKPFISSKQI LTM
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells.
  • 基因功能參考文獻:
    1. MECR is involved in mitochondrial fatty acid synthesis, and overexpression of this gene increases peroxisome proliferator-activated receptor alpha (PPARalpha) activity. PMID: 27845578
    2. results suggest that mutations in MECR cause a distinct human disorder of the mitochondrial fatty acid synthesis pathway; the observation of decreased lipoylation raises the possibility of a potential therapeutic strategy PMID: 27817865
    3. overexpression of MECR, the last step in the mitochondrial fatty acid synthesis (mtFASII) pathway, causes modulation of gene expression through the PPAR pathway. PMID: 24161390
    4. The crystal structure of this dimeric enzyme (at 2.4 A resolution) suggests that the binding site for the recognition helix of the acyl carrier protein is in a groove between the two adjacent monomers. PMID: 18479707
  • 相關疾病:
    Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities (DYTOABG)
  • 亞細胞定位:
    [Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm. Nucleus.
  • 蛋白家族:
    Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
  • 組織特異性:
    Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.
  • 數據庫鏈接:

    HGNC: 19691

    OMIM: 608205

    KEGG: hsa:51102

    STRING: 9606.ENSP00000263702

    UniGene: Hs.183646



主站蜘蛛池模板: 护士的小嫩嫩好紧好爽| 丁香五月欧美成人| 夜夜高潮夜夜爽国产伦精品| 亚欧美无遮挡hd高清在线视频| 久久久久久av无码免费网站下载| 国产欧美日韩综合视频专区| 暖暖视频 免费 日本社区| 国产99爱在线视频免费观看| 麻花传媒在线mv免费观看视频| 99久久久无码国产精品秋霞网| 成人av久久一区二区三区| 999精品无码a片在线1级| 6080yyy午夜理论片中无码| 丰满多毛的大隂户毛茸茸| 久久亚洲中文无码咪咪爱| 国产精品久久久久久影视不卡| 精品无码无人网站免费视频| 国产a三级久久精品| 国内免费视频成人精品| 国产日产久久高清欧美一区| 五级黄高潮片90分钟视频| 午夜福利影院私人爽爽| 亚洲欧洲日产国码无码| 精品午夜福利1000在线观看| 日本特黄特黄刺激大片| 精品无码久久久久国产电影 | 亚洲老熟女性亚洲| 欧美国产激情18| 无码人妻精品中文字幕不卡| 国内午夜熟妇又乱又伦| 亚洲日韩aⅴ在线视频 | 色先锋av资源中文字幕| 伊人久久大香线蕉综合直播| 免费观看男女性高视频| 欧美另类videossexo高潮| 久久婷婷五月综合色国产香蕉| 无码精品日韩专区| 国产精品福利视频导航| 四房播播开心五月| 亚洲丁香五月激情综合 | 天堂www天堂在线资源|