在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MECR Antibody

  • 中文名稱:
    MECR兔多克隆抗體
  • 貨號:
    CSB-PA013639GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    MECR
  • 別名:
    AI195831 antibody; CGI 63 antibody; FASN2B antibody; Homolog of yeast 2 enoyl thioester reductase antibody; HsNrbf-1 antibody; HsNrbf1 antibody; mecr antibody; MECR_HUMAN antibody; Mitochondrial 2 enoyl thioester reductase antibody; mitochondrial antibody; NRBF 1 antibody; NRBF-1 antibody; NRBF1 antibody; Nuclear receptor binding factor 1 antibody; Nuclear receptor-binding factor 1 antibody; OTTMUSP00000009996 antibody; RP23-13A13.1 antibody; Trans 2 enoyl CoA reductase; mitochondrial antibody; Trans-2-enoyl-CoA reductase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human MECR
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Displays a preference for medium-chain over short- and long-chain substrates. May provide the octanoyl chain used for lipoic acid biosynthesis, regulating protein lipoylation and mitochondrial respiratory activity particularly in Purkinje cells.
  • 基因功能參考文獻:
    1. MECR is involved in mitochondrial fatty acid synthesis, and overexpression of this gene increases peroxisome proliferator-activated receptor alpha (PPARalpha) activity. PMID: 27845578
    2. results suggest that mutations in MECR cause a distinct human disorder of the mitochondrial fatty acid synthesis pathway; the observation of decreased lipoylation raises the possibility of a potential therapeutic strategy PMID: 27817865
    3. overexpression of MECR, the last step in the mitochondrial fatty acid synthesis (mtFASII) pathway, causes modulation of gene expression through the PPAR pathway. PMID: 24161390
    4. The crystal structure of this dimeric enzyme (at 2.4 A resolution) suggests that the binding site for the recognition helix of the acyl carrier protein is in a groove between the two adjacent monomers. PMID: 18479707
  • 相關疾病:
    Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities (DYTOABG)
  • 亞細胞定位:
    [Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm. Nucleus.
  • 蛋白家族:
    Zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily
  • 組織特異性:
    Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.
  • 數據庫鏈接:

    HGNC: 19691

    OMIM: 608205

    KEGG: hsa:51102

    STRING: 9606.ENSP00000263702

    UniGene: Hs.183646



主站蜘蛛池模板: 综合久久给合久久狠狠狠97色 | av色综合久久天堂av色综合在| 亚洲精品美女久久久久99| 国内午夜国产精品小视频| 亚洲精品伊人久久久大香| 久久午夜羞羞影院免费观看| 亚洲精品国产精品乱码视色| 国产sm调教折磨视频失禁| 精品无码成人片一区二区 | 亚洲a∨无码无在线观看| 黑人好猛厉害爽受不了好大撑| 97国产揄拍国产精品人妻| 欧美亚洲高清国产| 国产天美传媒性色av| 免费观看又污又黄在线观看| 97se亚洲国产综合自在线尤物| 无尺码精品产品国产| 久久国产精品久久久久久| 激情综合五月| 十八禁真人啪啪免费网站| 美女露出奶头扒开尿口视频直播| 中文字幕在线播放| 国产亚洲精品久久久ai换| 无码东京热一区二区三区| 亚洲精品gv天堂无码男同| 国产sm调教折磨视频| 亚洲gv天堂gv无码男同| 欧美性色老妇人| 国产亚洲精品俞拍视频| 亚洲精品成人a在线观看| 亚洲精品久久国产精品浴池 | 熟女人妇 成熟妇女系列视频| 少妇人妻综合久久中文字幕| 极品少妇扒开粉嫩小泬视频| 亚洲欧美日韩v在线观看不卡| 精品人伦一区二区三区蜜桃免费| 精品久久久久中文字幕加勒比| 久久午夜无码鲁丝片直播午夜精品| 亚洲v欧美v国产v在线观看| 亚洲天堂2017无码| 国产av国片精品一区二区|