Recombinant Human Thrombospondin type-1 domain-containing protein 4 (THSD4), partial

中文名稱：

人THSD4重組蛋白
貨號：

CSB-YP744393HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人THSD4重組蛋白
貨號：

CSB-EP744393HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人THSD4重組蛋白
貨號：

CSB-EP744393HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人THSD4重組蛋白
貨號：

CSB-BP744393HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人THSD4重組蛋白
貨號：

CSB-MP744393HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

THSD4
Uniprot No.：

Q6ZMP0
別名：

THSD4; UNQ9334/PRO34005; Thrombospondin type-1 domain-containing protein 4; A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6; ADAMTS-like protein 6; ADAMTSL-6
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.
基因功能參考文獻(xiàn)：
1. In breast cancer, some GATA3 effects shift from tumor suppressing to tumor promoting during tumorigenesis, with deregulation of three genes, BCL2, DACH1, THSD4, representing major GATA3-controlled processes in cancer progression. PMID: 25410484
2. ADAMTSL6beta has a role in fibrillin-1 microfibril formation PMID: 21880733
3. THSD4 polymorphism was not found to be associated with COPD risk PMID: 21965014
4. Variations may be important determinants of osteoporosis in Japanese women. PMID: 18488137
亞細(xì)胞定位：

Secreted, extracellular space, extracellular matrix.
數(shù)據(jù)庫鏈接：

HGNC: 25835

OMIM: 614476

KEGG: hsa:79875

STRING: 9606.ENSP00000261862

UniGene: Hs.387057